Evidence map›Paper›PMID 38187683›Full record

ArticlebioRxiv : the preprint server for biology2023

Machine Learning and Metabolic Model Guided CRISPRi Reveals a Central Role for Phosphoglycerate Mutase in

Niaz Bahar Chowdhury, Nick Pokorzynski, Elizabeth A Rucks, Scot P Ouellette, Rey A Carabeo, Rajib Saha

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Niaz Bahar ChowdhuryChemical and Biomolecular Engineering, University of Nebraska-Lincoln, Lincoln, Nebraska, 68508, USA.
Nick PokorzynskiDepartment of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, Nebraska, 68198, USA.ORCID 0000-0003-2438-2368
Elizabeth A RucksDepartment of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, Nebraska, 68198, USA.
Scot P OuelletteDepartment of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, Nebraska, 68198, USA.
Rey A CarabeoDepartment of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, Nebraska, 68198, USA.ORCID 0000-0002-5708-5493
Rajib SahaChemical and Biomolecular Engineering, University of Nebraska-Lincoln, Lincoln, Nebraska, 68508, USA.ORCID 0000-0002-2974-0243
University of Nebraska Medical Center · USUniversity of Nebraska–Lincoln · US

Funding

Regulatory Role of Tandem Tryptophan Codons in Chlamydial PersistenceR01AI132406 · NIAID · WASHINGTON STATE UNIVERSITY · PI CARABEO, REY A, OUELLETTE, SCOT P · 2019 to 2023
$2.9M
A Predictive Modeling Framework to Dissect the Dynamic Immunometabolic Responses to Pathogenic infection and the Kinetic Reprogramming of Metabolism in Cancer Cell SystemR35GM143009 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI SAHA, RAJIB · 2021 to 2025
$1.8M
NIAID NIH HHS R01 AI132406NIGMS NIH HHS R35 GM143009
6 · The paper itself

Abstract

Upon nutrient starvation,

Indexed as

C. trachomatisglobal stress responsemetabolic bottlenecknutrient starvationpersistence

Identifiers

PMID38187683
PMCPMC10769294
OpenAlexW4389913774

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.