Evidence map›Paper›PMID 38187668›Full record

ArticlebioRxiv : the preprint server for biology2023

Homological landscape of human brain functional sub-circuits.

Duy Duong-Tran, Ralph Kaufmann, Jiong Chen, Xuan Wang, Sumita Garai, Frederick Xu, Jingxuan Bao, Enrico Amico, Alan David Kaplan, Giovanni Petri and 3 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 3 countries.

Duy Duong-TranDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, PA, USA.
Ralph KaufmannDepartment of Mathematics, Purdue University, West Lafayette, IN, USA.
Jiong ChenDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, PA, USA.
Xuan WangDepartment of Electrical and Computer Engineering, George Mason University, Fairfax, VA, USA.
Sumita GaraiDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, PA, USA.
Frederick XuDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, PA, USA.
Jingxuan BaoDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, PA, USA.
Enrico AmicoNeuro-X Institute, EPFL, Geneva, Switzerland.
Alan David KaplanComputational Engineering Division, Lawrence Livermore National Laboratory, Livermore, CA, USA.
Giovanni PetriCENTAI Institute, 10138 Torino, Italy.
Joaquin GoniPurdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, Indiana, USA.
Yize ZhaoSchool of Public Health, Yale University, New Heaven, CT, USA.
Li ShenDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, PA, USA.
University of Pennsylvania · USPurdue University West Lafayette · USGeorge Mason University · USIMT School for Advanced Studies Lucca · ITLawrence Livermore National Laboratory · USUnited States Naval Academy · USUniversity of Geneva · CHYale University · US

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
Ultrascale Machine Learning to Empower Discovery in Alzheimers Disease BiobanksU01AG068057 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Christos Davatzikos, Heng Huang · 2020 to 2026
$20.7M
Translational big data analytic approaches to advance drug repurposing for Alzheimer's diseaseR01AG071470 · NIA · UNIVERSITY OF PENNSYLVANIA · PI KIM, DOKYOON, NING, XIA · 2021 to 2025
$3.8M
Novel integrative imaging genetics analysis for Alzheimer's disease riskand progressionRF1AG068191 · NIA · YALE UNIVERSITY · PI ZHAO, YIZE · 2021 to 2021
$1.9M
Cross-disciplinary training in translational neuroimaging of ADRDT32AG076411 · NIA · UNIVERSITY OF PENNSYLVANIA · PI JOHN A DETRE, MURRAY GROSSMAN · 2022 to 2026
$1.5M
NIA NIH HHS R01 AG071470NIA NIH HHS RF1 AG068191NIA NIH HHS T32 AG076411NIA NIH HHS U01 AG068057NIMH NIH HHS U54 MH091657
6 · The paper itself

Abstract

Human whole-brain functional connectivity networks have been shown to exhibit both local/quasilocal (e.g., set of functional sub-circuits induced by node or edge attributes) and non-local (e.g., higher-order functional coordination patterns) properties. Nonetheless, the non-local properties of topological strata induced by local/quasilocal functional sub-circuits have yet to be addressed. To that end, we proposed a homological formalism that enables the quantification of higher-order characteristics of human brain functional sub-circuits. Our results indicated that each homological order uniquely unravels diverse, complementary properties of human brain functional sub-circuits. Noticeably, the

Identifiers

PMID38187668
PMCPMC10769445
OpenAlexW4390143501

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.