Evidence map›Paper›PMID 38187650›Full record

ArticlebioRxiv : the preprint server for biology2023

Activated PI3Kδ specifically perturbs mouse Treg homeostasis and function leading to immune dysregulation.

Akhilesh K Singh, Fahd Al Qureshah, Travis Drow, Baidong Hou, David J Rawlings

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 4 countries.

Akhilesh K SinghCenter for Immunity and Immunotherapy, Seattle Children's Research Institute, Seattle, WA.
Fahd Al QureshahCenter for Immunity and Immunotherapy, Seattle Children's Research Institute, Seattle, WA.
Travis DrowCenter for Immunity and Immunotherapy, Seattle Children's Research Institute, Seattle, WA.
Baidong HouKey Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
David J RawlingsCenter for Immunity and Immunotherapy, Seattle Children's Research Institute, Seattle, WA.
Center for Infectious Disease Research · USChinese Academy of Sciences · CNKing Abdulaziz City for Science and Technology · SA

Funding

An integrated strategy to define the functional and synergistic impact of T1D causal variantsDP3DK111802 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI RAWLINGS, DAVID J · 2016 to 2016
$4.4M
NIDDK NIH HHS DP3 DK111802
6 · The paper itself

Abstract

Foxp3

Identifiers

PMID38187650
PMCPMC10769388
OpenAlexW4390139699

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.