Evidence map›Paper›PMID 38187602›Full record

ArticlebioRxiv : the preprint server for biology2023

Mucus polymer concentration and

Matthew A Greenwald, Suzanne L Meinig, Lucas M Plott, Cristian Roca, Matthew G Higgs, Nicholas P Vitko, Matthew R Markovetz, Kaitlyn R Rouillard, Jerome Carpenter, Mehmet Kesimer and 3 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Matthew A Greenwald
Suzanne L Meinig
Lucas M Plott
Cristian Roca
Matthew G HiggsORCID 0000-0002-5460-4980
Nicholas P Vitko
Matthew R Markovetz
Kaitlyn R RouillardORCID 0000-0002-0856-8640
Jerome Carpenter
Mehmet Kesimer
David B HillORCID 0000-0002-9270-777X
Jonathan C Schisler
Matthew C WolfgangORCID 0000-0003-4534-6470
University of North Carolina at Chapel Hill · US

Funding

Impact of hyperglycemia on the pathogenesis of chronic bacterial lung infectionR21AI174088 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI THURLOW, LANCE R., WOLFGANG, MATTHEW C · 2023 to 2024
$411k
NIAID NIH HHS R21 AI174088
6 · The paper itself

Abstract

The airway milieu of individuals with muco-obstructive airway diseases (MADs) is defined by the accumulation of dehydrated mucus due to hyperabsorption of airway surface liquid and defective mucociliary clearance. Pathological mucus becomes progressively more viscous with age and disease severity due to the concentration and overproduction of mucin and accumulation of host-derived extracellular DNA (eDNA). Respiratory mucus of MADs provides a niche for recurrent and persistent colonization by respiratory pathogens, including Importance: Antibiotic treatment failure in

Identifiers

PMID38187602
PMCPMC10769284
OpenAlexW4390079714

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.