Evidence map›Paper›PMID 38187599›Full record

ArticlebioRxiv : the preprint server for biology2023

Comparative basolateral amygdala connectomics reveals dissociable single-neuron projection patterns to frontal cortex in macaques and mice.

Zachary R Zeisler, Kelsey A Heslin, Frederic M Stoll, Patrick R Hof, Roger L Clem, Peter H Rudebeck

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Zachary R ZeislerNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.ORCID 0000-0003-1371-497X
Kelsey A HeslinNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.ORCID 0000-0003-1615-9334
Frederic M StollNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.ORCID 0000-0002-8642-8133
Patrick R HofNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.ORCID 0000-0002-3208-1154
Roger L ClemNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.ORCID 0000-0002-8965-9455
Peter H RudebeckNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.ORCID 0000-0002-1411-7555

Funding

Cellular substrates of early life traumaR01MH124880 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CLEM, ROGER L · 2020 to 2024
$2.8M
Comparative Neuroanatomy at single-neuron resolutionR34NS122050 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CLEM, ROGER L, RUDEBECK, PETER · 2021 to 2021
$758k
NIMH NIH HHS R01 MH124880NINDS NIH HHS R34 NS122050
6 · The paper itself

Abstract

The basolateral amygdala (BLA) projects to the frontal cortex (FC) in both rodents and primates, but the comparative organization of single-neuron BLA-FC projections is unknown. Using a barcoded connectomic approach, we found that BLA neurons are more likely to project to multiple distinct parts of FC in mice than in macaques. Further, while single BLA neuron projections to nucleus accumbens are similarly organized in mice and macaques, BLA-FC connections differ.

Indexed as

Amygdalacomparativeconnectomicsfrontal cortexhumanmacaquemouseneuroanatomyprojections

Identifiers

PMID38187599
PMCPMC10769239

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.