Evidence map›Paper›PMID 38187590›Full record

ArticlebioRxiv : the preprint server for biology2023

Structure of an insect gustatory receptor.

Heather M Frank, Sanket Walujkar, Richard M Walsh, Willem J Laursen, Douglas L Theobald, Paul A Garrity, Rachelle Gaudet

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Heather M FrankDepartment of Molecular and Cellular Biology, Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA.ORCID 0000-0001-6822-6338
Sanket WalujkarDepartment of Molecular and Cellular Biology, Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA.ORCID 0000-0002-5892-4578
Richard M WalshThe Harvard Cryo-EM Center for Structural Biology, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-8939-8988
Willem J LaursenDepartment of Biology and Volen Center for Complex Systems, Brandeis University, Waltham, MA 02453, USA.ORCID 0000-0002-0952-317X
Douglas L TheobaldDepartment of Biochemistry, Brandeis University, Waltham, MA 02453, USA.ORCID 0000-0002-2695-8343
Paul A GarrityDepartment of Biology and Volen Center for Complex Systems, Brandeis University, Waltham, MA 02453, USA.ORCID 0000-0002-8274-6564
Rachelle GaudetDepartment of Molecular and Cellular Biology, Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA.ORCID 0000-0002-9177-054X
Harvard University · USBrandeis University · US

Funding

Evolution of enzyme structure and function viewed at atomic resolutionR01GM096053 · NIGMS · BRANDEIS UNIVERSITY · PI Douglas Lowell Theobald · 2011 to 2026
$3.6M
The molecular and cellular basis of short-range host cue sensing in mosquito vectorsR01AI157194 · NIAID · BRANDEIS UNIVERSITY · PI GARRITY, PAUL · 2020 to 2024
$3.3M
Mechanism of Divalent Metal Transport by NRamp-Family TransportersR01GM120996 · NIGMS · HARVARD UNIVERSITY · PI GAUDET, RACHELLE · 2017 to 2024
$3.0M
Towards molecular mechanisms of invertebrate Gustatory ReceptorsR21DC018497 · NIDCD · BRANDEIS UNIVERSITY · PI GARRITY, PAUL, GAUDET, RACHELLE · 2020 to 2021
$453k
NIAID NIH HHS R01 AI157194NIDCD NIH HHS R21 DC018497NIGMS NIH HHS R01 GM096053NIGMS NIH HHS R01 GM120996
6 · The paper itself

Abstract

Gustatory Receptors (GRs) are critical for insect chemosensation and are potential targets for controlling pests and disease vectors. However, GR structures have not been experimentally determined. We present structures of

Indexed as

7TMICchemoreceptorchemosensationcryogenic electron microscopygustationligand-gated ion channelseven transmembrane ion channeltaste

Identifiers

PMID38187590
PMCPMC10769236
OpenAlexW4389966266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.