Evidence map›Paper›PMID 38187567›Full record

ArticlebioRxiv : the preprint server for biology2023

Robust trigger wave speed in

Jo-Hsi Huang, Yuping Chen, William Y C Huang, Saman Tabatabaee, James E Ferrell

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Jo-Hsi HuangDepartment of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305-5174, USA.ORCID 0000-0003-1221-7285
Yuping ChenDepartment of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305-5174, USA.ORCID 0000-0002-9819-0230
William Y C HuangDepartment of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305-5174, USA.ORCID 0000-0002-6061-8887
Saman TabatabaeeDepartment of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305-5174, USA.
James E FerrellDepartment of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305-5174, USA.ORCID 0000-0003-4767-3926

Funding

Cytoplasmic organization and systems-level function in Xenopus extractsR35GM131792 · NIGMS · STANFORD UNIVERSITY · PI JAMES E. FERRELL · 2019 to 2026
$5.6M
Reconstructing and deconstructing intracellular signaling at the membrane-cytosol interfaceK99GM143481 · NIGMS · STANFORD UNIVERSITY · PI HUANG, YUAN-CHI · 2022 to 2023
$200k
NIGMS NIH HHS K99 GM143481NIGMS NIH HHS R35 GM131792
6 · The paper itself

Abstract

Self-regenerating trigger waves can spread rapidly through the crowded cytoplasm without diminishing in amplitude or speed, providing consistent, reliable, long-range communication. The macromolecular concentration of the cytoplasm varies in response to physiological and environmental fluctuations, raising the question of how or if trigger waves can robustly operate in the face of such fluctuations. Using

Indexed as

Cytoplasmdiffusionmolecular crowdingpositive feedback looprate coefficientreaction-diffusion systemrobustnessscaling relationshipsignal transductionXenopus egg extract

Identifiers

PMID38187567
PMCPMC10769400

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.