Evidence map›Paper›PMID 38187544›Full record

ArticlebioRxiv : the preprint server for biology2023

Amyloid precursor protein induces reactive astrogliosis.

Gretsen Velezmoro Jauregui, Dragana Vukić, Isaac G Onyango, Carlos Arias, Jan S Novotný, Kateřina Texlová, Shanshan Wang, Kristina Locker Kovačovicova, Natalie Polakova, Jana Zelinkova and 11 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors at 9 institutions in 7 countries.

Gretsen Velezmoro JaureguiTranslational Ageing and Neuroscience Program, Centre for Translational Medicine, International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic.
Dragana VukićCentral European Institute of Technology, Masaryk University, Brno, Czech Republic.
Isaac G OnyangoTranslational Ageing and Neuroscience Program, Centre for Translational Medicine, International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic.
Carlos AriasDepartment of Neurosciences, University of California San Diego, La Jolla, CA, USA.
Jan S NovotnýInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic.
Kateřina TexlováTranslational Ageing and Neuroscience Program, Centre for Translational Medicine, International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic.
Shanshan WangVeterans Affairs San Diego Healthcare System, San Diego, USA.
Kristina Locker KovačovicovaPsychoGenics, Paramus, USA.
Natalie PolakovaInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic.
Jana ZelinkovaInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic.
Maria ČarnaInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic.
Valentina Lacovich StrašilCentral European Institute of Technology, Masaryk University, Brno, Czech Republic.
Brian P HeadVeterans Affairs San Diego Healthcare System, San Diego, USA.
Daniel HavasPsychoGenics, Paramus, USA.
Martin MistrikInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic.
Robert ZorecLaboratory of Neuroendocrinology - Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Alexei VerkhratskyFaculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Liam KeeganCentral European Institute of Technology, Masaryk University, Brno, Czech Republic.ORCID 0000-0001-7915-5790
Mary O'ConnelCentral European Institute of Technology, Masaryk University, Brno, Czech Republic.ORCID 0000-0003-3844-6174
Robert RissmanDepartment of Neurosciences, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0001-9245-8278
Gorazd B StokinTranslational Ageing and Neuroscience Program, Centre for Translational Medicine, International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic.ORCID 0000-0001-8430-8755
Institute of Molecular and Translational Medicine · CZCentral European Institute of Technology · CZUniversity Hospital Brno · CZPsychogenics (United States) · USUniversity of California San Diego · USUniversity of San Diego · USGloucestershire Hospitals NHS Foundation Trust · GBIkerbasque · ESUniversity of Ljubljana · SI

Funding

UCSD Shiley-Marcos Alzheimer's Disease Research Center P30P30AG062429 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DOUGLAS R GALASKO · 2019 to 2026
$34.9M
BLRD VA I01 BX003671BLRD VA IK6 BX006318NIA NIH HHS P30 AG062429
6 · The paper itself

Abstract

We present

Indexed as

amyloid precursor proteinastrocytesinterferon pathwaylipopolysaccharidereactive astrogliosistraumatic brain injury

Identifiers

PMID38187544
PMCPMC10769227
OpenAlexW4389914727

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.