Evidence map›Paper›PMID 38187156›Full record

ArticleFrontiers in neurology2023

Predictors of aneurysm shrinkage after flow diversion treatment for internal carotid artery aneurysms: quantitative volume analysis with MRI.

Ryo Akiyama, Akira Ishii, Takayuki Kikuchi, Masakazu Okawa, Yukihiro Yamao, Yu Abekura, Isao Ono, Natsuhi Sasaki, Hirofumi Tsuji, So Matsukawa and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06541275 (Assessment of the Dynamic Reduction in Volume and Prolonged Shrinkage of Giant and Symptomatic Cerebral Aneurysms Following Combined Endovascular Interventions), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06541275 enrolling by invitationnot on this mapstarted 2024, after this paper: background citation

Assessment of the Dynamic Reduction in Volume and Prolonged Shrinkage of Giant and Symptomatic Cerebral Aneurysms Following Combined Endovascular Interventions

TypeobservationalSponsorNational Centre for Neurosurgery, Republic of KazakhstanRan2024 to 2026Enrolled102ConditionsBrain AneurysmArmsbrain MRI and CT
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ryo AkiyamaDepartment of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Akira IshiiDepartment of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Takayuki KikuchiDepartment of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Masakazu OkawaDepartment of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yukihiro YamaoDepartment of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yu AbekuraDepartment of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Isao OnoDepartment of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Natsuhi SasakiDepartment of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Hirofumi TsujiDepartment of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
So MatsukawaDepartment of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Susumu MiyamotoDepartment of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Kyoto University · JPHikone Central Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Although aneurysm shrinkage often occurs after flow diversion treatment for intracranial aneurysms, no reports have addressed the factors associated with aneurysm shrinkage. Materials and methods: This retrospective single-center study was performed to examine patients with unruptured internal carotid artery aneurysms who were treated using flow diversion and followed up by imaging for at least 12 months. The study outcome was aneurysm shrinkage (volume reduction of ≥10%) 12 months after treatment. Aneurysm volume was quantitatively assessed using the MRIcroGL software. Patient and aneurysm characteristics were statistically analyzed. Results: This study involved 81 patients with 88 aneurysms. At the 6 months, 12 months, and last follow-ups, the proportion of aneurysms that had shrunk was 50, 64, and 65%, respectively. No adjunctive coiling (odds ratio, 56.7; 95% confidence interval, 7.03-457.21; Conclusion: The rate of aneurysm shrinkage after flow diversion increased during the first 12 months after treatment, but not thereafter. No adjunctive coiling and aneurysm occlusion were predictors of aneurysm shrinkage, respectively. If adjunctive coiling is required, a volume embolization rate of ≤15.5% may be suggested for aneurysm regression.

Indexed as

aneurysmflow diversionMRIshrinkagevolume analysis

Identifiers

PMID38187156
PMCPMC10768176
OpenAlexW4390055896

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.