ArticleCureus2024
The Influence of Anthropometrics on Cardiac Mechanics in Healthy Women With Opposite Obesity Phenotypes (Android vs Gynoid).
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 5 citations in OpenAlex.
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- Mortality and cardiovascular risk of triglyceride-glucose and derived indices in cardiovascular-kidney-metabolic syndrome stages 0-3: a dose-response meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Preoperative Magnetic Resonance Imaging-Derived Adiposity Profiling and Cardiometabolic Remodeling After Metabolic and Bariatric Surgery.Obesity surgery · 2026Article
- Body Mass Index and LDL Cholesterol Across Controls, Hypertension, and Ischemic Heart Disease with Preserved Ejection Fraction: A Single-Center Retrospective Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Associations between cardiometabolic index and sleep disorders: Results from NHANES 2015 to 2020.Medicine · 2026Article
- Systolic Versus Diastolic Echocardiographic Assessment of Epicardial Adipose Tissue for the Detection of Obstructive Coronary Artery Disease: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Elevated homocysteine associated with higher cardiovascular risk in young patients with myocardial infarction: the role of metabolic phenotypes.Frontiers in endocrinology · 2026Article
- Association of obesity-metabolic indices with heart failure in patients with coronary artery disease: a multicenter retrospective observational study.Frontiers in endocrinology · 2026Observational
- Dietary branched-chain amino acids intake in relation to general and central obesity among Chinese children and adolescents: a cross-sectional study.Frontiers in nutrition · 2026Article
- The predictive value of surrogate insulin resistance indices for T2DM complicated with metabolic syndrome: a retrospective study based on hospitalized patients in China.Frontiers in endocrinology · 2026Article
- Association between TyG-related indices and in-hospital acute heart failure in patients with acute myocardial infarction after emergency percutaneous coronary intervention.Frontiers in endocrinology · 2026Article
- Systemic inflammatory response index is associated with increased all-cause and cardiovascular mortality in obstructive sleep apnea: evidence from NHANES and validation with an external hospital-based dataset.Frontiers in medicine · 2026Article
- Association of obesity-metabolic phenotypes with coronary artery disease prevalence: interaction and exploratory mediation analyses of high-sensitivity C-reactive protein.Frontiers in cardiovascular medicine · 2026Article
- Comprehensive Assessment of Biventricular and Biatrial Myocardial Strain Parameters at Six Years Postpartum in a Cohort of Women with Previous Hypertensive Disorders of Pregnancy.Journal of clinical medicine · 2025Article
- Comprehensive Assessment of Biventricular and Biatrial Myocardial Strain Parameters at 4 Years Postpartum in a Cohort of Women with Previous Gestational Diabetes Mellitus.Journal of clinical medicine · 2025Article
- Diastolic dysfunction in adults with uncomplicated obesity evaluated with left atrial and left ventricular tissue tracking and ventricular volume-time curve: a prospective cardiac magnetic resonance study.Quantitative imaging in medicine and surgery · 2024Article
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe possible influence exerted by mechanical factors and/or compressive phenomena on myocardial strain parameters in healthy individuals with opposite obesity phenotypes (android vs gynoid) has never been previously investigated. Accordingly, we aimed at evaluating the relationship between anthropometrics, such as the waist-to-hip ratio (WHR), modified Haller index (MHI, the ratio of chest transverse diameter over the distance between sternum and spine), and epicardial adipose tissue (EAT), and left ventricular (LV)-global longitudinal strain (GLS), in healthy women with opposite obesity phenotypes (android vs gynoid).
methodsForty healthy women with obesity (body mass index (BMI) ≥30 Kg/m
resultsCompared to the other groups of women, those with android obesity were found with significantly greater LVMi, higher LV filling pressures, and lower biventricular and biatrial deformation indices. A strong inverse correlation between LV-GLS and all anthropometrics (WHR, MHI, and EAT) was demonstrated in both groups of women with obesity. Univariate logistic regression analysis revealed that WHR (OR 1.58, 95%CI 1.22-2.03, p<0.001) and LVMi (OR 1.09, 95%CI 1.02-1.16, p=0.006) were independently correlated with LV-GLS impairment in women with android obesity. On multivariate logistic regression analysis, the WHR maintained a statistically significant association with the above-mentioned outcome (OR 1.68, 95%CI 1.14-2.48, p=0.009). Receiver operating characteristic (ROC) curve analysis showed that a WHR value ≥1.01 had 93% sensitivity and 100% specificity for detecting LV-GLS impairment in women with android obesity (AUC=0.98; 95%CI 0.96-1.00).
conclusionsAnthropometrics may strongly influence cardiac mechanics in healthy women with obesity. The WHR is associated with reduced LV-GLS magnitude in healthy women with android obesity, independent of age, glycometabolic status, and LV size.
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