Evidence map›Paper›PMID 38186961›Full record

ArticleBioactive materials2024

Conformationally regulated "nanozyme-like" cerium oxide with multiple free radical scavenging activities for osteoimmunology modulation and vascularized osseointegration.

Shusen Bao, Dongmei Yu, Zhen Tang, Hao Wu, Hao Zhang, Ning Wang, Yichao Liu, Hai Huang, Chaozong Liu, Xiaokang Li and 1 more

Abstract read
In one paragraph

Article in Bioactive materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Immunomodulatory Nanozymes as Programmable Redox-Immune Set-Point Regulators.Small (Weinheim an der Bergstrasse, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shusen BaoDepartment of Orthopedics, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China.
Dongmei YuDepartment of Orthopedics, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China.
Zhen TangDepartment of Orthopedics, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China.
Hao WuDepartment of Orthopedics, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China.
Hao ZhangDepartment of Burn Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, 710038, China.
Ning WangDepartment of Orthopedics, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China.
Yichao LiuDepartment of Orthopedics, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China.
Hai HuangDepartment of Orthopedics, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China.
Chaozong LiuUniversity College London, UCL Institute of Orthopaedics and Musculo-Skeletal Science, M14 the Royal National Orthopaedic Hospital, Stanmore, HA7 4LP, United Kingdom.
Xiaokang LiDepartment of Orthopedics, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China.
Zheng GuoDepartment of Orthopedics, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given post-operative aseptic loosening in orthopedic disease treatment, osteointegration occurs at the bone-implant interface as a holistic process, including immunoregulation (e.g., macrophage polarization), angiogenesis and osteogenesis in sequence. In order to achieve early rapid and satisfactory osseointegration, different nano-shaped (nanocone, nanopolyhedron and nanoflower abbr. NC, NP & NF) cerium oxide (CeO

Indexed as

Durable redox activationFree radical scavengingNanozyme-like” cerium oxideOsteoimmunology modulationVascularized osseointegration

Identifiers

PMID38186961
PMCPMC10770363

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.