Evidence map›Paper›PMID 38186472›Full record

ArticleCureus2023

Long COVID-19 Syndrome: Insights From a Major Tertiary Center in the UK on Who Is at Greater Risk.

Saad Tariq Khan, Khalid Rashid, Farrukh Ansar, Muhammad Y Khan, Fahd Ali Khan, Rawan Ebrahim Husain Ahmed Ali Ismaeel, Raheem Hanif Mohammed, Rehan Mustafa, Bisma Tariq Khan, Behram Tariq and 2 more

Abstract read
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Saad Tariq KhanMedicine, Darlington Memorial Hospital, Darlington, GBR.
Khalid RashidGeneral Internal Medicine, James Cook University Hospital, Middlesbrough, GBR.
Farrukh AnsarMedicine, Northwest School of Medicine, Khyber Medical University, Peshawar, PAK.
Muhammad Y KhanMedical Education, Pak International Medical College, Peshawar, PAK.
Fahd Ali KhanMedicine, James Cook University Hospital, Middlesbrough, GBR.
Rawan Ebrahim Husain Ahmed Ali IsmaeelMedicine, James Cook University Hospital, Middlesbrough, GBR.
Raheem Hanif MohammedMedicine, James Cook University Hospital, Middlesbrough, GBR.
Rehan MustafaMedicine, James Cook University Hospital, Middlesbrough, GBR.
Bisma Tariq KhanMedicine, Shaukat Khanum Memorial Hospital and Research Centre, Lahore, PAK.
Behram TariqMedicine, James Cook University Hospital, Middlesbrough, GBR.
Mubbashar HusssainMedicine, James Cook University Hospital, Middlesbrough, GBR.
Aamir WaheedInternal Medicine, Northampton General Hospital, Northampton, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe COVID-19 pandemic triggered the unprecedented 'long COVID' crisis, with persistent symptoms beyond two months post-infection. This study explores the nexus between long COVID symptoms, patient demographics such as age, gender, and smoking, and clinical factors like vaccination, disease severity, and comorbidities.

methodsA retrospective analysis of records was conducted between September 2021 and December 2022. The analysis covered adults with confirmed COVID-19 diagnoses. Data encompassed demographics, medical history, vaccination, disease severity, hospitalization, treatments, and post-COVID symptoms, analyzed using logistic regression.

resultsAmong 289 participants, the average age was 51.51 years. Around 62.6% were females, and 93% received the COVID-19 vaccination, i.e., primarily the mRNA vaccine (48.4%) and the adenovirus vector-based vaccine (34.8%). Reinfections occurred in 11.76% of cases. Disease severity varied, with 75% having mild, 15% having moderate, and 10% having severe infections. Hospitalization rates were significant (25.6%), including 10.7% requiring intensive care. Thirteen distinct post-COVID symptoms were reported. Fatigue, shortness of breath upon exertion, and brain fog emerged as the most prevalent symptoms. Notably, females exhibited higher symptom prevalence. Significant correlations were established between higher BMI and smoking with augmented symptomatology. Conversely, a link between booster doses and symptom reduction was discerned. Using multinomial regression analysis, gender and smoking were identified as predictors of post-COVID-19 symptoms.

conclusionThe study underscores obesity, smoking, and the female gender's impact on long COVID symptoms; boosters show promise in alleviation. Respiratory pathology might underlie persistent symptoms in cases with radiological abnormalities and abnormal spirometry. Findings contribute to risk stratification, intervention strategies, and further research.

Indexed as

covid-19covid-19 vaccinelong covid-19post-covid-19 symptomspredictors of post covid-19 syndrome

Identifiers

PMID38186472
PMCPMC10767765

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.