Evidence map›Paper›PMID 38186347›Full record

ArticleHaematologica2024

Acute myeloid leukemia-driven IL-3-dependent upregulation of BCL2 in non-malignant hematopoietic stem and progenitor cells increases venetoclax-induced cytopenias.

Dominic J Fowler-Shorten, Rebecca S Maynard, Katherine Hampton, Annalisa Altera, Matthew Markham, Martha Ehikioya, Edyta E Wojtowicz, Kristian M Bowles, Stuart A Rushworth, Charlotte Hellmich

Open access · goldAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Haematologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Dominic J Fowler-ShortenNorwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UQ.
Rebecca S MaynardNorwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UQ.
Katherine HamptonNorwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UQ.
Annalisa AlteraNorwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UQ.
Matthew MarkhamNorwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UQ.
Martha EhikioyaNorwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UQ.
Edyta E WojtowiczEarlham Institute, Norwich Research Park, Norwich, NR4 7UH.
Kristian M BowlesNorwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UQ, United Kingdom; Department of Haematology, Norfolk and Norwich University Hospital NHS Trust, Colney Lane, Norwich, NR4 7UY.
Stuart A RushworthNorwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UQ. s.rushworth@uea.ac.uk.
Charlotte HellmichNorwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UQ, United Kingdom; Department of Haematology, Norfolk and Norwich University Hospital NHS Trust, Colney Lane, Norwich, NR4 7UY. c.hellmich@uea.ac.uk.
Norwich Research Park · GBUniversity of East Anglia · GB

Funding

Medical Research Council MR/T02934X/1Wellcome Trust 213731/Z/18/ZWellcome Trust 220534/Z/20/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bridged Bicyclo Compounds, HeterocyclicHematopoietic Stem CellsInterleukin-3Leukemia, Myeloid, AcuteProto-Oncogene Proteins c-bcl-2SulfonamidesAntineoplastic AgentsCytopeniaHumansUp-RegulationAntineoplastic AgentsBCL2 protein, humanBridged Bicyclo Compounds, HeterocyclicIL3 protein, humanInterleukin-3Proto-Oncogene Proteins c-bcl-2Sulfonamidesvenetoclax

Identifiers

PMID38186347
PMCPMC11063845
OpenAlexW4390533076

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.