Evidence map›Paper›PMID 38185902›Full record

ReviewJournal of human nutrition and dietetics : the official journal of the British Dietetic Association2025

The evolution of nutritional care in children and young people with acute lymphoblastic leukaemia: a narrative review.

Amy L Lovell, Breeana Gardiner, Louise Henry, Jessica M Bate, Mark F H Brougham, Raquel Revuelta Iniesta

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06846294 (OBesity PREVention in Children and Young People Treated with ALLtogetheR), which is not on this map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
8.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06846294 nanot yet recruitingnot on this map

OBesity PREVention in Children and Young People Treated with ALLtogetheR: Prehabilitation Feasibility Intervention

TypeinterventionalSponsorUniversity of ExeterRan2025 to 2029Enrolled90ConditionsDiet Intervention, Physical Activity Intervention, Standard Care ControlArmsDiet, Diet and physical activity
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Nutrition and physical activity interventions delivered to children and young people during cancer treatment: a systematic literature review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Childhood cancer and future cardiometabolic health.npj metabolic health and disease · 2026
    Review
  6. Development and validation of a nutrition risk screening for patients with childhood cancer in Brazil (NUTRICCAN).Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026
    Article
  7. Review
  8. The evolution of nutritional care in children and young people with acute lymphoblastic leukaemia: a narrative review.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 2 countries.

Amy L LovellDepartment of Nutrition and Dietetics, The University of Auckland, Faculty of Medical and Health Sciences, Auckland, New Zealand.ORCID http://orcid.org/0000-0002-1708-9633
Breeana GardinerDepartment of Nutrition and Dietetics, Great Ormond Street Hospital NHS Foundation Trust, London, UK.ORCID http://orcid.org/0000-0002-8700-9643
Louise HenryDepartment of Nutrition and Dietetics, Royal Marsden NHS Foundation Trust, Surrey, UK.
Jessica M BateDepartment of Paediatric Oncology, Southampton Children's Hospital, Southampton, UK.
Mark F H BroughamDepartment of Haematology and Oncology, Royal Hospital for Sick Children, Edinburgh, UK.
Raquel Revuelta IniestaChildren's Health and Exercise Research Centre (CHERC), Faculty of Health and Life Sciences, Public Health and Sport Sciences, Medical School, St Luke's Campus, University of Exeter, Exeter, UK.ORCID http://orcid.org/0000-0002-5534-7146
Great Ormond Street Hospital for Children NHS Foundation Trust · GBRoyal Hospital for Children · GBRoyal Marsden NHS Foundation Trust · GBSouthampton Children's Hospital · GBUniversity of Auckland · NZUniversity of Exeter · GB

Funding

None
6 · The paper itself

Abstract

backgroundAcute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy in the world. Advances in treatment protocols have resulted in survival rates of >80% in most high-income countries (HIC); however, children and young people (CYP) with ALL continue to face significant nutrition-related challenges during treatment.

methodsThis narrative review outlines the changing landscape of treatment and survivorship for CYP with ALL and the advances in nutrition knowledge that call for changes to clinical nutrition practice.

resultsThe incidence of ALL has remained stable in HIC; however, there have been significant advances in survival over the past 30 years. Overweight and obesity are increasingly prevalent in CYP with ALL at diagnosis, during treatment and in survivorship. Coupled with poor diet quality, high-energy and saturated fat intakes, altered eating behaviours and inactivity, this necessitates the need for a shift in nutrition intervention. Undernutrition remains a concern for CYP with high-risk treatment protocols where oral or enteral nutrition support remains a cornerstone of maintaining nutrition status.

conclusionsWith improved treatment protocols and high survival rates, a shift to focusing on diet quality, prevention of excessive weight gain and obesity during treatment and survivorship is necessary.

Indexed as

Nutritional StatusPrecursor Cell Lymphoblastic Leukemia-LymphomaAdolescentChildChild, PreschoolDietFemaleHumansMaleMalnutritionNutrition TherapyYoung Adultacute lymphoblastic leukaemiachildhood cancernutrition assessmentnutrition interventionnutrition status

Identifiers

PMID38185902
PMCPMC11589404
OpenAlexW4390666245

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.