Evidence map›Paper›PMID 38185820›Full record

ArticleApplied and environmental microbiology2024

Use of CRISPR interference for efficient and rapid gene inactivation in

Peng Zhou, Bibek G C, Flynn Stolte, Chenggang Wu

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Gene Silencing by CRISPR Interference in Fusobacterium nucleatum.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Inactivation of thebioRxiv : the preprint server for biology · 2025
    Article
  12. Review
  13. Development of a conditional plasmid for gene deletion in non-modelApplied and environmental microbiology · 2025
    Article
  14. Potential and application ofFrontiers in microbiology · 2025
    Article
  15. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Peng ZhouDepartment of Microbiology & Molecular Genetics, The University of Texas Health Science Center, Houston, Texas, USA.
Bibek G CDepartment of Microbiology & Molecular Genetics, The University of Texas Health Science Center, Houston, Texas, USA.
Flynn StolteDepartment of Microbiology & Molecular Genetics, The University of Texas Health Science Center, Houston, Texas, USA.
Chenggang WuDepartment of Microbiology & Molecular Genetics, The University of Texas Health Science Center, Houston, Texas, USA.ORCID 0000-0002-5700-7188
The University of Texas Health Science Center at Houston · US

Funding

Regulation in Fusobacterium-mediated coaggregationR01DE030895 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI WU, CHENGGANG · 2021 to 2025
$1.7M
NIDCR NIH HHS R01 DE030895
6 · The paper itself

Abstract

Gene inactivation by creating in-frame deletion mutations in

Indexed as

FusobacteriumFusobacterium nucleatumRiboswitchGene SilencingRNA, Guide, CRISPR-Cas SystemsTheophyllineRiboswitchRNA, Guide, CRISPR-Cas SystemsTheophyllineCRISPRiessential geneFusobacterium nucleatumgene inactivationriboswitch

Identifiers

PMID38185820
PMCPMC10880640
OpenAlexW4390665357

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.