Evidence map›Paper›PMID 38185779›Full record

ArticleInsights into imaging2024

Imaging phenotyping using

Linyi Zhou, Jinju Sun, He Long, Weicheng Zhou, Renxiang Xia, Yi Luo, Jingqin Fang, Yi Wang, Xiao Chen

Open access · goldAbstract read
In one paragraph

Article in Insights into imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  6. BMC medical imaging · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Linyi ZhouDepartment of Nuclear Medicine, Daping Hospital, Army Medical University, Chongqing, China.
Jinju SunDepartment of Nuclear Medicine, Daping Hospital, Army Medical University, Chongqing, China.
He LongDepartment of Nuclear Medicine, Daping Hospital, Army Medical University, Chongqing, China.
Weicheng ZhouDepartment of Nuclear Medicine, Daping Hospital, Army Medical University, Chongqing, China.
Renxiang XiaDepartment of Nuclear Medicine, Daping Hospital, Army Medical University, Chongqing, China.
Yi LuoDepartment of Nuclear Medicine, Daping Hospital, Army Medical University, Chongqing, China.
Jingqin FangDepartment of Ultrasound, Daping Hospital, Army Medical University, Chongqing, China. jingqin0405@163.com.
Yi WangDepartment of Nuclear Medicine, Daping Hospital, Army Medical University, Chongqing, China. ywhxl@qq.com.
Xiao ChenDepartment of Nuclear Medicine, Daping Hospital, Army Medical University, Chongqing, China. xiaochen229@foxmail.com.ORCID http://orcid.org/0000-0002-8647-0614
Army Medical University · CN

Funding

RESEARCH TRAINING IN COGNITIVE AGINGT32AG000175 · NIA · GEORGIA INSTITUTE OF TECHNOLOGY · PI DUARTE, AUDREY · 1988 to 2020
$5.6M
Chongqing Clinical Research Centre of Imaging and Nuclear Medicine CSTC2015YFPT-gcjsyjzx0175Chongqing Science and Health Joint Medical Research Project-Young and Middle-aged High-level Talent Project 2023GDRC002Natural Science Foundation of Chongqing cstc2019jcyj-msxmX0123Science and Technology Innovation Ability Enhancement Project of Army Medical University 2022XJS29
6 · The paper itself

Abstract

objectivesTo develop and validate a machine learning model using

methodsEight hundred and forty-six patients who underwent preoperative PET/CT with pathologically confirmed adenocarcinoma were enrolled. After segmentation, 1688 radiomics features were extracted from PET/CT and selected to construct predictive models. Then, we developed a nomogram based on PET/CT radiomics integrated with clinical features. Receiver operating curves, calibration curves, and decision curve analysis (DCA) were performed for diagnostics assessment and test of the developed models for distinguishing patients with MP/S components from the patients without.

resultsPET/CT radiomics-clinical combined model could well distinguish patients with MP/S components from those without MP/S components (AUC = 0.87), which performed better than PET (AUC = 0.829, p < 0.05) or CT (AUC = 0.827, p < 0.05) radiomics models in the training cohort. In test cohorts, radiomics-clinical combined model outperformed the PET radiomics model in test cohort 1 (AUC = 0.859 vs 0.799, p < 0.05) and the CT radiomics model in test cohort 2 (AUC = 0.880 vs 0.829, p < 0.05). Calibration curve indicated good coherence between all model prediction and the actual observation in training and test cohorts. DCA revealed PET/CT radiomics-clinical model exerted the highest clinical benefit.

conclusion

Indexed as

Computed tomographyLung adenocarcinomaMachine learningPositron emission tomographyRadiomics

Identifiers

PMID38185779
PMCPMC10772036
OpenAlexW4390655853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.