Evidence map›Paper›PMID 38184889›Full record

ArticleAIDS care2024

Prevalence and risk factors of detectable HIV viral load among pregnant women with HIV infection seeking antenatal care in Southern Malawi.

Felix A Mkandawire, Andrea Buchwald, Nginache Nampota-Nkomba, Osward M Nyirenda, Kingsley Zuze, Shiphrah Kuria, Cristiana Cairo, Miriam K Laufer

Open access · greenAbstract read
In one paragraph

Article in AIDS care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Felix A MkandawireBlantyre Malaria Project, Kamuzu University of Health Sciences, College of Medicine, Blantyre, Malawi.
Andrea BuchwaldCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA.
Nginache Nampota-NkombaBlantyre Malaria Project, Kamuzu University of Health Sciences, College of Medicine, Blantyre, Malawi.
Osward M NyirendaBlantyre Malaria Project, Kamuzu University of Health Sciences, College of Medicine, Blantyre, Malawi.
Kingsley ZuzeBlantyre Malaria Project, Kamuzu University of Health Sciences, College of Medicine, Blantyre, Malawi.
Shiphrah KuriaAmref International University, Nairobi, Kenya.
Cristiana CairoInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
Miriam K LauferCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA.
Kamuzu University of Health SciencesUniversity of Maryland, Baltimore · USAmref Health Africa · KE

Funding

Neurocognitive development of HIV-exposed and uninfected infants in MalawiR01HD100235 · NICHD · UNIVERSITY OF MARYLAND BALTIMORE · PI GLADSTONE, MELISSA, LAUFER, MIRIAM K. · 2020 to 2024
$3.3M
The impact of in utero HIV exposure on infant T and B cell responses in MalawiU01HD092308 · NICHD · UNIVERSITY OF MARYLAND BALTIMORE · PI CAIRO, CRISTIANA, LAUFER, MIRIAM K. · 2017 to 2021
$2.7M
Long-term neurocognitive outcomes of HIV-exposed uninfected childrenR33HD103066 · NICHD · UNIVERSITY OF MARYLAND BALTIMORE · PI GLADSTONE, MELISSA, LAUFER, MIRIAM K. · 2022 to 2024
$2.4M
Mentoring in patient-oriented research in global healthK24AI114996 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI LAUFER, MIRIAM K. · 2016 to 2025
$1.6M
Long-term neurocognitive outcomes of HIV-exposed uninfected childrenR61HD103066 · NICHD · UNIVERSITY OF MARYLAND BALTIMORE · PI GLADSTONE, MELISSA, LAUFER, MIRIAM K. · 2020 to 2021
$745k
Dissecting the causal impact of prenatal HIV exposure and the postnatal environment on development in Malawian InfantsK01MH134741 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI BUCHWALD, ANDREA G. · 2023 to 2025
$468k
NIAID NIH HHS K24 AI114996NICHD NIH HHS R01 HD100235NICHD NIH HHS R33 HD103066NICHD NIH HHS R61 HD103066NICHD NIH HHS U01 HD092308NIMH NIH HHS K01 MH134741
6 · The paper itself

Abstract

We evaluated detectable viral load (VL) in pregnant women established on antiretroviral therapy (ART) for at least 6 months before conception and those self-reported as ART naïve at first antenatal care (ANC) at two government clinics in Southern Malawi. We used logistic regression to identify the predictors of detectable viral load (VL), defined as any measure greater than 400 copies/ml. Of 816 women, 67.9% were established on ART and 32.1% self-reported as ART naïve. Among women established on ART, 10.8% had detectable VL and 9.9% had VL >1000 copies/ml (WHO criteria for virological failure). In adjusted analysis, among women established on ART, virological failure was associated with younger age (

Indexed as

adherenceHIV infectionHIV suppressionMalawipregnancySDG 3: good health and well-being

Identifiers

PMID38184889
PMCPMC11227598
OpenAlexW4390651645

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.