Evidence map›Paper›PMID 38184525›Full record

SynthesisBMC urology2024

Incidence of renal cell carcinoma after solid organ transplantation: a systematic review and meta-analysis.

Chang Xu, Hefeng Geng, Yannan Li, Fang Sun, Huiwei Sun, Yingshi Zhang, Qingchun Zhao

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chang XuTeaching Hospital of Shenyang Pharmaceutical University, General Hospital of Northern Theater Command, Shenyang, 100083, P.R. China.
Hefeng GengTeaching Hospital of Shenyang Pharmaceutical University, General Hospital of Northern Theater Command, Shenyang, 100083, P.R. China.
Yannan LiDepartment of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, P.R. China.
Fang SunInstitute of Infectious Disease, Department of Infectious Disease, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, P.R. China.
Huiwei SunInstitute of Infectious Disease, Department of Infectious Disease, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, P.R. China.
Yingshi ZhangTeaching Hospital of Shenyang Pharmaceutical University, General Hospital of Northern Theater Command, Shenyang, 100083, P.R. China. 755085862@qq.com.
Qingchun ZhaoTeaching Hospital of Shenyang Pharmaceutical University, General Hospital of Northern Theater Command, Shenyang, 100083, P.R. China. zhaoqingchun1967@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence rate of malignant tumors after solid organ transplantation is higher than the normal population. The aim of our study is to identify the risk of renal cell carcinoma (RCC) after liver, kidney, heart and lung transplantation, respectively, and suggest that transplant patients can be screened early for tumors to avoid risk.

methodsPubMed, Embase and the Cochrane Library from their inception until August 16,2023. Retrospective and cohort studies which focus on the statistical data of standardized incidence ratios (SIRs) of RCC after solid organ transplantation (SOT) more than one year have been included and extracted. The study was registered with PROSPERO, CRD4202022343633.

resultsSixteen original studies have been included for meta-analysis. Liver transplantation could increase the risk of RCC (SIR = 0.73, 95%CI: 0.53 to 0.93) with no heterogeneity(P = 0.594, I

conclusionLiver, kidney, heart and lung transplantation patients have an increased risk of processing RCC compared to the general population and most subgroups, especially in geographic location of European subgroup, which suggested that patients should be screened frequently after transplantation.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsKidney TransplantationHumansIncidenceRetrospective StudiesIncidence of renal cell carcinomaMalignant incidenceMeta-analysisSolid organ transplantationSystematic review

Identifiers

PMID38184525
PMCPMC10771683

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.