Evidence map›Paper›PMID 38184493›Full record

ArticleBrain structure & function2024

Sulcal variability in anterior lateral prefrontal cortex contributes to variability in reasoning performance among young adults.

Ethan H Willbrand, Samantha Jackson, Szeshuen Chen, Catherine B Hathaway, Willa I Voorhies, Silvia A Bunge, Kevin S Weiner

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In one paragraph

Article in Brain structure & function, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Variable Presence of an Evolutionarily New Brain Structure Is Related to Trait Impulsivity.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026
    Article
  3. Anchoring Functional Connectivity to Individual Sulcal Morphology Yields Insights in a Pediatric Study of Reasoning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  4. Article
  5. Article
  6. Emotion-related impulsivity is related to orbitofrontal cortical sulcation.Cortex; a journal devoted to the study of the nervous system and behavior · 2024
    Article
  7. Article
  8. Article
  9. Defining Overlooked Structures Reveals New Associations between the Cortex and Cognition in Aging and Alzheimer's Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ethan H WillbrandMedical Scientist Training Program, School of Medicine and Public Health, University of WI-Madison, Madison, WI, USA.
Samantha JacksonHelen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, USA.
Szeshuen ChenDepartment of Psychology, University of California, Berkeley, Berkeley, CA, USA.
Catherine B HathawayCognitive Science, University of California, Berkeley, Berkeley, CA, USA.
Willa I VoorhiesDepartment of Psychology, University of California, Berkeley, Berkeley, CA, USA.
Silvia A Bunge *Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, USA. sbunge@berkeley.edu.
Kevin S Weiner *Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, USA. kweiner@berkeley.edu.
University of California, Berkeley · USUniversity of Wisconsin–Madison · US

Funding

NIH HHS MSTP Grant T32 GM140935
6 · The paper itself

Abstract

Identifying structure-function correspondences is a major goal among biologists, cognitive neuroscientists, and brain mappers. Recent studies have identified relationships between performance on cognitive tasks and the presence or absence of small, shallow indentations, or sulci, of the human brain. Building on the previous finding that the presence of the ventral para-intermediate frontal sulcus (pimfs-v) in the left anterior lateral prefrontal cortex (aLPFC) was related to reasoning task performance in children and adolescents, we tested whether this relationship extended to a different sample, age group, and reasoning task. As predicted, the presence of this aLPFC sulcus was also associated with higher reasoning scores in young adults (ages 22-36). These findings have not only direct developmental, but also evolutionary relevance-as recent work shows that the pimfs-v is exceedingly rare in chimpanzees. Thus, the pimfs-v is a key developmental, cognitive, and evolutionarily relevant feature that should be considered in future studies examining how the complex relationships among multiscale anatomical and functional features of the brain give rise to abstract thought.

Indexed as

Prefrontal CortexProblem SolvingAdolescentBrainBrain MappingChildHumansMagnetic Resonance ImagingTask Performance and AnalysisYoung AdultComparative biologyCortical foldingMRINeuroanatomyPrefrontal cortexReasoning

Identifiers

PMID38184493
OpenAlexW4390636028

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.