ArticleInternational dental journal2024
Effects of Propolis-Based Herbal Toothpaste on Dentine Hypersensitivity.
Article in International dental journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Home-use agents in the treatment of dentin hypersensitivity: clinical effectiveness evaluation with different measurement methods.Clinical oral investigations · 2025Trial
- Protective effects of herbal toothpastes against dentin erosion: an in vitro study.Scientific reports · 2026Article
- Effect of eggshell nanoparticles and fluoride varnish, with and without diode laser, on dentinal tubule occlusion (An in vitro study).BMC oral health · 2026Article
- Evaluation of Propolis as an Intracanal Agent in Combination with an Nd:YAG Laser for Bacterial Reduction.Journal of lasers in medical sciences · 2026Article
- Comparison of Herbal and Potassium Nitrate Toothpastes in Managing Dentin Hypersensitivity: A Randomized Controlled Trial.Dentistry journal · 2025Article
- Article
- Comparison of casein phosphopeptide-amorphous calcium phosphate fluoride paste and a propolis-containing herbal toothpaste in dentinal hypersensitivity: A randomized trial.Dental research journal · 2025Article
- In vitro study of the treatment of dentin hypersensitivity with gallic acid combined with sodium fluoride.BMC oral health · 2024Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe objective of this in vitro study was to compare the effectiveness of a propolis-based herbal toothpaste with 5% sodium fluoride varnishin obstructing human dentinal tubules; Scanning electron microscopy was utilised to obtain quantitative and qulitative data on tubular obstruction.
methodsThirty-nine extracted human premolar teeth were collected. The cementum layer was removed using a water-cooled diamond bur and the smear layer using ethylenediaminetetraacetic acid (EDTA) 17%. Then, the samples were randomly divided into 3 groups (n = 13 each), as follows: group 1: dentin discs exposed to the propolis-based herbal toothpaste (Herbex); group 2: dentin discs exposed to 5% sodium fluoride varnish; and group 3: control. Then, all discs were observed and imaged in 4 non-overlapping fields by an electron microscope at 2000× magnification. The topography and number of open, closed, and semi-closed tubules were counted in all images. The data were analysed using Kruskal-Wallis test, Mann-Whitney U test, and Friedman test. The statistical analysis was performed with SPSS statistic 22.0 software, with a significance level of α = 0.05.
resultsIn pairwise comparisons of the groups considering the percentage of open, closed, and semi-closed tubules, the difference was not statistically significant between the 5% sodium fluoride varnish and propolis groups in the closed and semi-closed tubules, but it was statistically significant with the control group. Additionally, the percentage of open tubules in the propolis-based herbal toothpaste group was significantly lower than in the 5% sodium fluoride varnish and control group.
conclusionsBoth propolis-based herbal toothpaste and 5% sodium fluoride varnish is effective in blocking human dentin tubules to various extents.
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Registered trials
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