Evidence map›Paper›PMID 38183658›Full record

ArticleChemical research in toxicology2024

Chemotherapeutic Mechanism of Action of the Synthetic Resorcinolic Methyl 3,5-dimethoxy-2-octanoylbenzoate.

Willian Ayala Correa, Silvia Cordeiro das Neves, Rodrigo Juliano Oliveira, Cândida A Kassuya, Stephanie D Navarro, Allana Cristina Faustino Martins, Baby Saroja, Barbara Mitsuyasu, Ingridhy Ostaciana Maia Freitas da Silveira, Neimar Vitor and 6 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical research in toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Willian Ayala CorreaInstitute of Chemistry, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul 79070-900, Brazil.
Silvia Cordeiro das NevesStem Cell, Cell Therapy and Toxicological Genetics Research Centre (CeTroGen), Medical School, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul 79080-190, Brazil.
Rodrigo Juliano OliveiraStem Cell, Cell Therapy and Toxicological Genetics Research Centre (CeTroGen), Medical School, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul 79080-190, Brazil.
Cândida A KassuyaSchool of Health Sciences, Federal University of Grande Dourados, Dourados, Mato Grosso do Sul 79804-970, Brazil.
Stephanie D NavarroInstitute of Chemistry, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul 79070-900, Brazil.
Allana Cristina Faustino MartinsDepartment of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota 58102, United States.ORCID 0000-0001-5647-2187
Baby SarojaDepartment of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota 58102, United States.
Barbara MitsuyasuDepartment of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota 58102, United States.
Ingridhy Ostaciana Maia Freitas da SilveiraDepartment of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota 58102, United States.
Neimar VitorInstitute of Chemistry, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul 79070-900, Brazil.
Henrique Rodrigues Scherer CoelhoStem Cell, Cell Therapy and Toxicological Genetics Research Centre (CeTroGen), Medical School, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul 79080-190, Brazil.
Marcelo L B VilelaInstitute of Chemistry, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul 79070-900, Brazil.
Valter A do NascimentoGraduate Program in Health and Development in the Midwest Region, Medical School, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul 79070-900, Brazil.
Dênis P de LimaInstitute of Chemistry, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul 79070-900, Brazil.ORCID 0000-0002-6023-4867
Adilson BeatrizInstitute of Chemistry, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul 79070-900, Brazil.ORCID 0000-0001-6864-6092
Roberto da Silva GomesDepartment of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota 58102, United States.
Universidade Federal de Mato Grosso do Sul · BRNorth Dakota State University · USUniversidade Federal da Grande Dourados · BR

Funding

Targeting CLEC-2/podoplanin as a therapeutic strategy for pancreatic cancerP20GM109024 · NIGMS · NORTH DAKOTA STATE UNIVERSITY · PI Sanku Mallik · 2016 to 2026
$20.5M
NIGMS NIH HHS P20 GM109024
6 · The paper itself

Abstract

Resorcinolic lipids are described as potential examples of selective chemotherapeutic adjuvants that can enhance the effects of cyclophosphamide (

Indexed as

DNAAnimalsCell DeathComet AssayCyclophosphamideMaleMiceMolecular Docking SimulationCyclophosphamideDNA

Identifiers

PMID38183658
PMCPMC11987490
OpenAlexW4390635910

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.