Evidence map›Paper›PMID 38183420›Full record

ArticleJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2024

Phototoxicity of cyclometallated Ir(III) complexes bearing a thio-bis-benzimidazole ligand, and its monodentate analogue, as potential PDT photosensitisers in cancer cell killing.

Marta Martínez-Alonso, Callum G Jones, James D Shipp, Dimitri Chekulaev, Helen E Bryant, Julia A Weinstein

Open access · hybridAbstract read
In one paragraph

Article in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. DNA-Binding Properties of Iridium(III) Complexes Encompassing Design, Function and Biophysical Assessments.Chemphyschem : a European journal of chemical physics and physical chemistry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Marta Martínez-AlonsoDepartment of Chemistry, University of Sheffield, Sheffield, S3 7HF, UK.ORCID 0000-0002-0931-5274
Callum G JonesDepartment of Chemistry, University of Sheffield, Sheffield, S3 7HF, UK.ORCID 0000-0003-2958-8322
James D ShippDepartment of Chemistry, University of Sheffield, Sheffield, S3 7HF, UK.ORCID 0000-0002-0452-8895
Dimitri ChekulaevDepartment of Chemistry, University of Sheffield, Sheffield, S3 7HF, UK.
Helen E BryantDepartment of Oncology and Metabolism, Medical School, The University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK. h.bryant@sheffield.ac.uk.ORCID 0000-0003-2720-7020
Julia A WeinsteinDepartment of Chemistry, University of Sheffield, Sheffield, S3 7HF, UK. julia.weinstein@sheffield.ac.uk.ORCID 0000-0001-6883-072X
University of Sheffield · GB

Funding

Wellcome TrustWellcome Trust WT093134AIA
6 · The paper itself

Abstract

Two novel cyclometallated iridium(III) complexes have been prepared with one bidentate or two monodentate imidazole-based ligands, 1 and 2, respectively. The complexes showed intense emission with long lifetimes of the excited state. Femtosecond transient absorption experiments established the nature of the lowest excited state as

Indexed as

BenzimidazolesNeoplasmsPhotochemotherapyCell DeathCell Line, TumorIridiumLigandsPhotosensitizing AgentsBenzimidazolesbis-benzimidazoleIridiumLigandsPhotosensitizing AgentsAnticancer drugsIridiumPDTPhototoxicity

Identifiers

PMID38183420
PMCPMC11001735
OpenAlexW4390638504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.