Evidence map›Paper›PMID 38183131›Full record

ReviewEuropean journal of medical research2024

Radiopharmaceuticals: navigating the frontier of precision medicine and therapeutic innovation.

Shivang Dhoundiyal, Shriyansh Srivastava, Sachin Kumar, Gaaminepreet Singh, Sumel Ashique, Radheshyam Pal, Neeraj Mishra, Farzad Taghizadeh-Hesary

Open access · goldAbstract readReview
In one paragraph

Review in European journal of medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
49.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 123 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Chemical science · 2026
    Article
  5. Review
  6. Biomaterials for biomarker imaging and detection.Journal of advanced research · 2026
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Synthesis and in vitro characterization of [EJNMMI radiopharmacy and chemistry · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Shivang DhoundiyalDepartment of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, 203201, India.
Shriyansh SrivastavaDepartment of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, 203201, India. shriyanshsrivastav@gmail.com.
Sachin KumarDepartment of Pharmacology, Delhi Pharmaceutical Sciences and Research University (DPSRU), Sector 3 Pushp Vihar, New Delhi, 110017, India.
Gaaminepreet SinghDepartment of Physiology and Biophysics, Case Western Reserve University (CWRU), Cleveland, OH, USA.
Sumel AshiqueDepartment of Pharmaceutical Sciences, Bengal College of Pharmaceutical Sciences & Research, Durgapur, 713212, West Bengal, India.
Radheshyam PalDepartment of Pharmacology, Pandaveswar School of Pharmacy, Pandaveswar, 713346, West Bengal, India.
Neeraj MishraAmity Institute of Pharmacy, Amity University Madhya Pradesh, Gwalior, 474005, MP, India.
Farzad Taghizadeh-HesaryENT and Head and Neck Research Center and Department, The Five Senses Health Institute, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Farzadth89@gmail.com.ORCID http://orcid.org/0000-0002-6195-2203
Galgotias University · INCase Western Reserve University · USDelhi Pharmaceutical Science and Research University · INIran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review article explores the dynamic field of radiopharmaceuticals, where innovative developments arise from combining radioisotopes and pharmaceuticals, opening up exciting therapeutic possibilities. The in-depth exploration covers targeted drug delivery, delving into passive targeting through enhanced permeability and retention, as well as active targeting using ligand-receptor strategies. The article also discusses stimulus-responsive release systems, which orchestrate controlled release, enhancing precision and therapeutic effectiveness. A significant focus is placed on the crucial role of radiopharmaceuticals in medical imaging and theranostics, highlighting their contribution to diagnostic accuracy and image-guided curative interventions. The review emphasizes safety considerations and strategies for mitigating side effects, providing valuable insights into addressing challenges and achieving precise drug delivery. Looking ahead, the article discusses nanoparticle formulations as cutting-edge innovations in next-generation radiopharmaceuticals, showcasing their potential applications. Real-world examples are presented through case studies, including the use of radiolabelled antibodies for solid tumors, peptide receptor radionuclide therapy for neuroendocrine tumors, and the intricate management of bone metastases. The concluding perspective envisions the future trajectory of radiopharmaceuticals, anticipating a harmonious integration of precision medicine and artificial intelligence. This vision foresees an era where therapeutic precision aligns seamlessly with scientific advancements, ushering in a new epoch marked by the fusion of therapeutic resonance and visionary progress.

Indexed as

Precision MedicineRadiopharmaceuticalsArtificial IntelligenceHumansRadiopharmaceuticalsCancerDrug deliveryPositron emission tomographyRadiopharmaceuticalsSingle-photon emission computed tomography

Identifiers

PMID38183131
PMCPMC10768149
OpenAlexW4390632397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.