Evidence map›Paper›PMID 38183090›Full record

ReviewJournal of nanobiotechnology2024

Spotlight on therapeutic efficiency of green synthesis metals and their oxide nanoparticles in periodontitis.

Mohammad Kiarashi, Parham Mahamed, Nader Ghotbi, Azadeh Tadayonfard, Kamyar Nasiri, Parisa Kazemi, Ashkan Badkoobeh, Saman Yasamineh, Ali Joudaki

Abstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohammad KiarashiCollege of Dentistry, Lorestan University of Medical Sciences, Khorramabad, Iran.
Parham MahamedStudent Research Committee, Alborz University of Medical Sciences, Karaj, Iran.
Nader GhotbiGeneral Dentist, Isfahan Azad University, School of Dentistry, Isfahan, Iran.
Azadeh TadayonfardMaxillofacial prosthetics fellow, Postgraduate department of prosthodontics, Dental Faculty,Tehran University of Medical Sciences, Tehran, Iran.
Kamyar NasiriDepartment of Dentistry, Islamic Azad University of Medical Sciences, Tehran, Iran.
Parisa KazemiFaculty of Dentistry, Ilam University of Medical Sciences, Ilam, Iran.
Ashkan BadkoobehDepartment of Oral and Maxillofacial Surgery, School of Dentistry, Qom University of Medical Sciences, Qom, Iran.
Saman YasaminehAzad Researchers, Viro-Biotech, Tehran, Iran. Yassaman124@gmail.com.
Ali JoudakiDepartment of Oral and Maxillofacial Surgery, Lorestan University of Medical Sciences, Khorram Abad, Lorestan, Iran. Joudakic@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontitis, one of the most prevalent dental diseases, causes the loss of bone and gum tissue that hold teeth in place. Several bacteria, commonly present in clinically healthy oral cavities, may induce and perpetuate periodontitis when their concentration rises in the gingival sulcus. Antibacterial effect against various Gram-negative and Gram-positive bacteria, including pathogenic and drug-resistant ones, has been shown for several distinct transient metal and metal oxide NPs. Therefore, NPs may be used in biomedicine to treat periodontal problems and in nanotechnology to inhibit the development of microorganisms. Instead of using harmful chemicals or energy-intensive machinery, biosynthesis of metal and metal oxide nanoparticles (NPs) has been suggested. To produce metal and metal oxide NPs, the ideal technique is "Green" synthesis because of its low toxicity and safety for human health and the environment. Gold NPs (AuNPs) appear to be less toxic to mammalian cells than other nanometals because their antibacterial activity is not dependent on reactive oxygen species (ROS). AgNPs also possess chemical stability, catalytic activity, and superior electrical and thermal conductivity, to name a few of their other advantageous characteristics. It was observed that zinc oxide (ZnO) NPs and copper (Cu) NPs exhibited discernible inhibitory effects against gram-positive and gram-negative bacterial strains, respectively. ZnO NPs demonstrated bactericidal activity against the microorganisms responsible for periodontitis. Medications containing magnetic NPs are highly effective against multidrug-resistant bacterial and fungal infections. The titanium dioxide (TiO

Indexed as

Metal NanoparticlesPeriodontitisZinc OxideAnimalsAnti-Bacterial AgentsGoldHumansMammalsOxidesAnti-Bacterial AgentsGoldOxidesZinc OxideAntibacterialGreen synthesizeMetal nanoparticlesMetal oxide NanoparticlesPeriodontitis

Identifiers

PMID38183090
PMCPMC10770920

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.