Evidence map›Paper›PMID 38182985›Full record

ArticleBMC geriatrics2024

Comorbid health conditions and their impact on social isolation, loneliness, quality of life, and well-being in people with dementia: longitudinal findings from the IDEAL programme.

Serena Sabatini, Anthony Martyr, Anna Hunt, Laura D Gamble, Fiona E Matthews, Jeanette M Thom, Roy W Jones, Louise Allan, Martin Knapp, Christina Victor and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMC geriatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Review
  6. Multimorbidity in dementia: Current perspectives and future challenges.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 2 countries.

Serena SabatiniInstitute of Mental Health, School of Medicine, University of Nottingham, Nottingham, UK.ORCID 0000-0002-3618-6949
Anthony MartyrUniversity of Exeter Medical School, University of Exeter, Exeter, UK. A.Martyr@exeter.ac.uk.ORCID 0000-0002-1702-8902
Anna HuntUniversity of Exeter Medical School, University of Exeter, Exeter, UK.ORCID 0000-0001-7523-1792
Laura D GamblePopulation Health Sciences Institute, Newcastle University, Newcastle, UK.ORCID 0000-0001-8496-9705
Fiona E MatthewsPopulation Health Sciences Institute, Newcastle University, Newcastle, UK.ORCID 0000-0002-1728-2388
Jeanette M ThomFaculty of Medicine and Health, The University of Sydney, Sydney, Australia.ORCID 0000-0002-6575-3711
Roy W JonesResearch Institute for the Care of Older People (RICE), Bath, UK.ORCID 0000-0002-7953-5985
Louise AllanUniversity of Exeter Medical School, University of Exeter, Exeter, UK.ORCID 0000-0002-8912-4901
Martin KnappLondon School of Economics and Political Science, London, UK.ORCID 0000-0003-1427-0215
Christina VictorCollege of Health, Medicine and Life Sciences, Department of Health Sciences, Brunel University London, London, UK.ORCID 0000-0002-4213-3974
Claire PentecostInstitute of Mental Health, School of Medicine, University of Nottingham, Nottingham, UK.ORCID 0000-0003-2048-5538
Jennifer M RustedSchool of Psychology, University of Sussex, Brighton, UK.ORCID 0000-0002-1341-6334
Robin G MorrisKing's College Institute of Psychiatry, Psychology and Neuroscience, London, UK.ORCID 0000-0001-7767-5258
Linda ClareUniversity of Exeter Medical School, University of Exeter, Exeter, UK.ORCID 0000-0003-3989-5318
University of Exeter · GBNewcastle University · GBUniversity of Nottingham · GBBrunel University of London · GBKing's College London · GBLondon School of Economics and Political Science · GBThe Research Institute for the Care of Older People · GBThe University of Sydney · AUUniversity of Sussex · GB

Funding

Alzheimer's Society 348, AS-PR2-16-001
6 · The paper itself

Abstract

backgroundMost people with dementia have multiple health conditions. This study explores (1) number and type of health condition(s) in people with dementia overall and in relation to age, sex, dementia type, and cognition; (2) change in number of health conditions over two years; and (3) whether over time the number of health conditions at baseline is related to social isolation, loneliness, quality of life, and/or well-being.

methodsLongitudinal data from the IDEAL (Improving the experience of Dementia and Enhancing Active Life) cohort were used. Participants comprised people with dementia (n = 1490) living in the community (at baseline) in Great Britain. Health conditions using the Charlson Comorbidity Index, cognition, social isolation, loneliness, quality of life, and well-being were assessed over two years. Mixed effects modelling was used.

resultsOn average participants had 1.8 health conditions at baseline, excluding dementia; increasing to 2.5 conditions over two years. Those with vascular dementia or mixed (Alzheimer's and vascular) dementia had more health conditions than those with Alzheimer's disease. People aged ≥ 80 had more health conditions than those aged < 65 years. At baseline having more health conditions was associated with increased loneliness, poorer quality of life, and poorer well-being, but was either minimally or not associated with cognition, sex, and social isolation. Number of health conditions had either minimal or no influence on these variables over time.

conclusionsPeople with dementia in IDEAL generally had multiple health conditions and those with more health conditions were lonelier, had poorer quality of life, and poorer well-being.

Indexed as

Alzheimer DiseaseLonelinessCross-Sectional StudiesHumansMultimorbidityQuality of LifeSocial IsolationAlzheimer’s diseaseComorbidityIllnessesPhysical healthSocial network

Identifiers

PMID38182985
PMCPMC10768096
OpenAlexW4390609213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.