Evidence map›Paper›PMID 38182945›Full record

ArticleIntensive care medicine experimental2024

Mastering the brain in critical conditions: an update.

Chiara Robba, Elisa R Zanier, Carmen Lopez Soto, Soojin Park, Romain Sonneville, Raimund Helbolk, Aarti Sarwal, Virginia F J Newcombe, Mathieu van der Jagt, Jan Gunst and 10 more

Open access · goldAbstract read
In one paragraph

Article in Intensive care medicine experimental, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Observational
  6. Update on traumatic brain injury in the ICU.Current opinion in anaesthesiology · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 16 institutions in 8 countries.

Chiara Robba *Anesthesia and Intensive Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neurosciences, Genoa, Italy.
Elisa R Zanier *Department of Acute Brain and Cardiovascular Injury, Mario Negri Institute for Pharmacological Research IRCCS, Milan, Italy. elisa.zanier@marionegri.it.ORCID http://orcid.org/0000-0002-3011-8718
Carmen Lopez SotoDepartment of Critical Care, King's College Hospital NHS Foundation Trust, London, SE5 9RS, UK.
Soojin ParkDepartments of Neurology and Biomedical Informatics, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Romain SonnevilleDepartment of Intensive Care Medicine, Hôpital Bichat-Claude Bernard, Université Paris Cité, INSERM UMR 1137, IAME, APHP.Nord, Paris, France.
Raimund HelbolkNeurological Intensive Care Unit, Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Aarti SarwalWake Forest Baptist Health Center, Winston-Salem, NC, USA.
Virginia F J NewcombePACE Section, Department of Medicine, University of Cambridge, Cambridge, UK.
Mathieu van der JagtDepartment of Intensive Care Adults, Erasmus MC-University Medical Centre, Room Ne-415, PO BOX 2040, 3000 CA, Rotterdam, The Netherlands.
Jan GunstDepartment of Intensive Care Medicine, University Hospitals Leuven, Leuven, Belgium.
Tobias GaussDepartment of Anaesthesia and Intensive Care, Centre Hospitalier Universitaire Grenoble, Universitaire Grenoble Alpes, Grenoble, France.
Samy FigueiredoDepartment of Anaesthesiology and Critical Care Medicine, Bicêtre Hospital, Université Paris-Saclay, Assistance Publique des Hôpitaux de Paris, Équipe DYNAMIC, Inserm UMR 999, Le Kremlin-Bicêtre, France.
Jacques DuranteauDepartment of Anaesthesiology and Critical Care Medicine, Bicêtre Hospital, Université Paris-Saclay, Assistance Publique des Hôpitaux de Paris, Équipe DYNAMIC, Inserm UMR 999, Le Kremlin-Bicêtre, France.
Markus B SkrifvarsDepartment of Emergency Care and Services, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Carolina IaquanielloNeuroanesthesia and Intensive Care, Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Susanne MuehlschlegelDivision of Neurosciences Critical Care, Departments of Neurology and Anesthesiology/Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Victoria MetaxaDepartment of Critical Care, King's College Hospital NHS Foundation Trust, London, SE5 9RS, UK.
Claudio SandroniDepartment of Intensive Care, Emergency Medicine and Anaesthesiology, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
Giuseppe CiterioSchool of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Geert MeyfroidtDepartment of Intensive Care Medicine, University Hospitals Leuven, Leuven, Belgium.
Inserm · FRKing's College Hospital NHS Foundation Trust · GBKU Leuven · BEAtrium Health Wake Forest Baptist · USColumbia University · USErasmus MC · NLFondazione IRCCS Istituto Neurologico Carlo Besta · ITJohannes Kepler University of Linz · ATJohns Hopkins University · USMario Negri Institute for Pharmacological Research · ITOspedale Policlinico San Martino · ITUniversità Cattolica del Sacro Cuore · ITUniversité Claude Bernard Lyon 1 · FRUniversity of Cambridge · GBUniversity of Helsinki · FIUniversity of Milano-Bicocca · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute brain injuries, such as traumatic brain injury and ischemic and hemorragic stroke, are a leading cause of death and disability worldwide. While characterized by clearly distict primary events-vascular damage in strokes and biomechanical damage in traumatic brain injuries-they share common secondary injury mechanisms influencing long-term outcomes. Growing evidence suggests that a more personalized approach to optimize energy substrate delivery to the injured brain and prognosticate towards families could be beneficial. In this context, continuous invasive and/or non-invasive neuromonitoring, together with clinical evaluation and neuroimaging to support strategies that optimize cerebral blood flow and metabolic delivery, as well as approaches to neuroprognostication are gaining interest. Recently, the European Society of Intensive Care Medicine organized a 2-day course focused on a practical case-based clinical approach of acute brain-injured patients in different scenarios and on future perspectives to advance the management of this population. The aim of this manuscript is to update clinicians dealing with acute brain injured patients in the intensive care unit, describing current knowledge and clinical practice based on the insights presented during this course.

Indexed as

Acute brain injuryNeuroimagingNeuromonitoringOutcomePrognostication

Identifiers

PMID38182945
PMCPMC10770006
OpenAlexW4390607502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.