Evidence map›Paper›PMID 38182920›Full record

ArticleJournal of endocrinological investigation2024

Quantification of lipoproteins by proton nuclear magnetic resonance spectroscopy (

L Nattero-Chávez, M Insenser, N Amigó, S Samino, N Martínez-Micaelo, B Dorado Avendaño, A Quintero Tobar, H F Escobar-Morreale, M Luque-Ramírez

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Journal of endocrinological investigation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04950634 (Sexual Dimorphism in the Prevalence and Progression of Cardiovascular Autonomic Neuropathy in Patients With Type 1 Diabetes), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04950634 completednot on this map

Sexual Dimorphism in the Prevalence and Progression of Cardiovascular Autonomic Neuropathy in Patients With Type 1 Diabetes

TypeobservationalSponsorFundacion para la Investigacion Biomedica del Hospital Universitario Ramon y CajalRan2018 to 2025Enrolled320Conditionstype1diabetes
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

L Nattero-Chávez *Department of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal, Madrid, Spain. marialia.nattero@salud.madrid.org.ORCID http://orcid.org/0000-0002-9758-9397
M Insenser *Diabetes, Obesity and Human Reproduction Research Group, Universidad de Alcalá, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS) and Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain. mariarosa.insenser@salud.madrid.org.
N AmigóBiosfer Teslab, CIBERDEM, Madrid, Spain.
S SaminoBiosfer Teslab, CIBERDEM, Madrid, Spain.
N Martínez-MicaeloBiosfer Teslab, CIBERDEM, Madrid, Spain.
B Dorado AvendañoDepartment of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal, Madrid, Spain.
A Quintero TobarDiabetes, Obesity and Human Reproduction Research Group, Universidad de Alcalá, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS) and Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain.
H F Escobar-MorrealeDepartment of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal, Madrid, Spain.
M Luque-RamírezDepartment of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal, Madrid, Spain.
Universidad de Alcalá · ESCentro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas · ESHospital Universitario Ramón y Cajal · ES

Funding

Instituto de Salud Carlos III DEM21-PIM02Instituto de Salud Carlos III PI18/01122Instituto de Salud Carlos III PI22/00616
6 · The paper itself

Abstract

aimsTo assess if advanced characterization of serum glycoprotein and lipoprotein profile, measured by proton nuclear magnetic resonance spectroscopy (

methodsCross-sectional study (ClinicalTrials.gov Identifier: NCT04950634). CAN was diagnosed using Ewing's score. Advanced characterization of macromolecular complexes including glycoprotein and lipoprotein profiles in serum samples were measured by

resultsThree hundred and twenty-three patients were included (46% female, mean age and duration of diabetes of 41 ± 13 years and 19 ± 11 years, respectively). The overall prevalence of CAN was 28% [95% confidence interval (95%CI): 23; 33]. Glycoproteins such as N-acetylglucosamine/galactosamine and sialic acid showed strong correlations with inflammatory markers such as high-sensitive C-reactive protein, fibrinogen, IL-10, IL-6, and TNF-α. On the contrary, we did not find any association between the former and CAN. A stepwise binary logistic regression model (R

conclusionsWhen added to clinical variables,

Indexed as

BiomarkersDiabetes Mellitus, Type 1LipoproteinsProton Magnetic Resonance SpectroscopyAdultAutonomic Nervous System DiseasesCross-Sectional StudiesDiabetic NeuropathiesFemaleHumansMaleMiddle AgedPrognosisBiomarkersLipoproteinsAutonomic nervous systemCardioautonomic neuropathyGlycoprotein profileLipid profileLipoproteinsProton nuclear magnetic resonance spectroscopyTriglyceridesType 1 diabetes

Identifiers

PMID38182920
OpenAlexW4390630738

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.