Evidence map›Paper›PMID 38182815›Full record

ArticleEMBO reports2024

Functional and structural asymmetry suggest a unifying principle for catalysis in membrane-bound pyrophosphatases.

Jannik Strauss, Craig Wilkinson, Keni Vidilaseris, Orquidea M de Castro Ribeiro, Jianing Liu, James Hillier, Maximilian Wichert, Anssi M Malinen, Bernadette Gehl, Lars Jc Jeuken and 2 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EMBO reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. NaInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 5 countries.

Jannik StraussAstbury Centre for Structural and Molecular Biology, University of Leeds, LS2 9JT, Leeds, UK.ORCID http://orcid.org/0000-0001-7482-6567
Craig WilkinsonAstbury Centre for Structural and Molecular Biology, University of Leeds, LS2 9JT, Leeds, UK.
Keni VidilaserisMolecular and Integrative Biosciences, Biological and Environmental Sciences, University of Helsinki, 00100, Helsinki, Finland.ORCID http://orcid.org/0000-0002-6453-6600
Orquidea M de Castro RibeiroMolecular and Integrative Biosciences, Biological and Environmental Sciences, University of Helsinki, 00100, Helsinki, Finland.ORCID http://orcid.org/0000-0003-0746-6666
Jianing LiuMolecular and Integrative Biosciences, Biological and Environmental Sciences, University of Helsinki, 00100, Helsinki, Finland.
James HillierAstbury Centre for Structural and Molecular Biology, University of Leeds, LS2 9JT, Leeds, UK.
Maximilian WichertLeiden Institute of Chemistry, University Leiden, PO Box 9502, 2300 RA, Leiden, The Netherlands.ORCID http://orcid.org/0000-0002-5302-3105
Anssi M MalinenDepartment of Life Technologies, University of Turku, FIN-20014, Turku, Finland.
Bernadette GehlMolecular and Integrative Biosciences, Biological and Environmental Sciences, University of Helsinki, 00100, Helsinki, Finland.
Lars Jc JeukenLeiden Institute of Chemistry, University Leiden, PO Box 9502, 2300 RA, Leiden, The Netherlands.ORCID http://orcid.org/0000-0001-7810-3964
Arwen R PearsonInstitute for Nanostructure and Solid State Physics, Hamburg Centre for Ultrafast Imaging, Universität Hamburg, 22761, Hamburg, Germany.
Adrian GoldmanAstbury Centre for Structural and Molecular Biology, University of Leeds, LS2 9JT, Leeds, UK. adrian.goldman@helsinki.fi.ORCID http://orcid.org/0000-0001-8032-9700
University of Helsinki · FIUniversity of Leeds · GBLeiden University · NLUniversität Hamburg · DEUniversity of Turku · FI

Funding

Academy of Finland (AKA) 1322609Academy of Finland (AKA) 307775Academy of Finland (AKA) 308105Bundesministerium für Bildung und Forschung (BMBF) 05K16GU1Bundesministerium für Bildung und Forschung (BMBF) 05K19GU1Deutsche Forschungsgemeinschaft (DFG) EXC1074Deutsche Forschungsgemeinschaft (DFG) EXC2056EC | H2020 | PRIORITY 'Excellent science' | H2020 Marie Skłodowska-Curie Actions (MSCA) 722687UKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BB/M021610/1University of Leeds 110th Anniversary Research Scholarship
6 · The paper itself

Abstract

Membrane-bound pyrophosphatases (M-PPases) are homodimeric primary ion pumps that couple the transport of Na

Indexed as

PyrophosphatasesSodiumCatalysisMembranesPyrophosphatasesSodiumAsymmetryMechanismMembrane ProteinsPyrophosphatasesTime-resolved Crystallography

Identifiers

PMID38182815
PMCPMC10897367
OpenAlexW4390620043

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.