ArticleNature medicine2024
Soft robotic apparel to avert freezing of gait in Parkinson's disease.
Article in Nature medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effects of Wearable Devices on Parkinson Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials Within the International Classification of Functioning, Disability, and Health Framework.Journal of medical Internet research · 2026Pooled it
- The Effects of Digital Health Interventions on Motor Symptoms, Nonmotor Symptoms, and Quality of Life in Patients With Parkinson Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- Insights into Parkinson's Disease-Related Freezing of Gait Detection and Prediction Approaches: A Meta Analysis.Sensors (Basel, Switzerland) · 2024Pooled it
- Knowledge mapping and research trends of accidental falls in patients with Parkinson's disease from 2003 to 2023: a bibliometric analysis.Frontiers in neurology · 2024Pooled it
- From Striatum to Prescription: An Evidence-Based and Bayesian Framework for Neuromotor Rehabilitation in Parkinson's Disease.NeuroSci · 2026Review
- Biomechanical energy harvesting to improve post-stroke mobility.Nature communications · 2026Article
- Biomechanics-informed inertial tracking achieves the accuracy of marker-based kinematics.Nature communications · 2026Article
- Progress and perspectives in soft robotics for surgery and rehabilitation.Journal of robotic surgery · 2026Review
- Soft Robotics and Advanced Technologies for Minimally Invasive Bioprinting: The Future of Internal Organ Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Bimodal iontronic skins powered by edge intelligence for real-time collaborative interaction.National science review · 2026Article
- Freezing of Gait in Parkinson's Disease: A Scoping Review on the Path Towards Real-Time Therapies.Sensors (Basel, Switzerland) · 2026Article
- Mechanomedicine.Nature reviews bioengineering · 2026Article
- Subthalamic deep brain stimulation alleviates the gait sequence effect and freezing of gait in Parkinson's disease.Parkinsonism & related disorders · 2026Article
- A predictive model of joint dynamics and ground reaction force using only leg length, body mass, and walking cadence.PloS one · 2026Article
- Hip exoskeleton assistance with machine-learning-based state estimation improves gait kinematics of people with Parkinson's disease.Frontiers in robotics and AI · 2026Article
- A hip extensor-assistive soft exosuit training redistributes plantar pressure in older adults: a randomized controlled pilot trial.Frontiers in bioengineering and biotechnology · 2026Article
- Interaction-based rapid heuristic optimization of exoskeleton assistance during walking.Communications engineering · 2025Article
- Fabrication of Soft Robotics by Additive Manufacturing: From Materials to Applications.Chemical reviews · 2025Review
- Bioinspired Intelligent Soft Robotics: From Multidisciplinary Integration to Next-Generation Intelligence.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Wearable Robots for Rehabilitation and Assistance of Gait: A Narrative Review.Annals of rehabilitation medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Freezing of gait (FoG) is a profoundly disruptive gait disturbance in Parkinson's disease, causing unintended stops while walking. Therapies for FoG reveal modest and transient effects, resulting in a lack of effective treatments. Here we show proof of concept that FoG can be averted using soft robotic apparel that augments hip flexion. The wearable garment uses cable-driven actuators and sensors, generating assistive moments in concert with biological muscles. In this n-of-1 trial with five repeated measurements spanning 6 months, a 73-year-old male with Parkinson's disease and substantial FoG demonstrated a robust response to robotic apparel. With assistance, FoG was instantaneously eliminated during indoor walking (0% versus 39 ± 16% time spent freezing when unassisted), accompanied by 49 ± 11 m (+55%) farther walking compared to unassisted walking, faster speeds (+0.18 m s
Indexed as
Identifiers
38182783What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.