Teenager With Recurrent Ataxia, Ophthalmoplegia, and Encephalopathy Associated With Demyelination: From the National Multiple Sclerosis Society Case Conference Proceedings

Kelsey E Poisson, Scott D Newsome, Jennifer Graves, Scott S Zamvil, Lydia R Marcus

Open access · goldAbstract read

In one paragraph

Article in Neurology(R) neuroimmunology & neuroinflammation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.5field-weighted citation impact, top 39% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kelsey E PoissonFrom the Nationwide Children's Hospital (K.E.P.), Columbus, OH; Johns Hopkins University School of Medicine (S.D.N.), Baltimore, MD; University of California San Diego School of Medicine (J.G.); University of California, San Francisco (S.S.Z.); and Children's of Alabama (L.R.M.), Birmingham.

Scott D NewsomeFrom the Nationwide Children's Hospital (K.E.P.), Columbus, OH; Johns Hopkins University School of Medicine (S.D.N.), Baltimore, MD; University of California San Diego School of Medicine (J.G.); University of California, San Francisco (S.S.Z.); and Children's of Alabama (L.R.M.), Birmingham.ORCID 0000-0002-5284-4681

Jennifer GravesFrom the Nationwide Children's Hospital (K.E.P.), Columbus, OH; Johns Hopkins University School of Medicine (S.D.N.), Baltimore, MD; University of California San Diego School of Medicine (J.G.); University of California, San Francisco (S.S.Z.); and Children's of Alabama (L.R.M.), Birmingham.ORCID 0000-0003-1539-1940

Scott S ZamvilFrom the Nationwide Children's Hospital (K.E.P.), Columbus, OH; Johns Hopkins University School of Medicine (S.D.N.), Baltimore, MD; University of California San Diego School of Medicine (J.G.); University of California, San Francisco (S.S.Z.); and Children's of Alabama (L.R.M.), Birmingham.ORCID 0000-0003-2720-9915

Lydia R MarcusFrom the Nationwide Children's Hospital (K.E.P.), Columbus, OH; Johns Hopkins University School of Medicine (S.D.N.), Baltimore, MD; University of California San Diego School of Medicine (J.G.); University of California, San Francisco (S.S.Z.); and Children's of Alabama (L.R.M.), Birmingham.

Nationwide Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 15-year-old adolescent boy developed subacute ataxia, encephalopathy, ophthalmoplegia, and dysarthria following a sore throat. An MRI examination revealed multifocal enhancing and nonenhancing supratentorial white matter and symmetric brainstem lesions. After 2 additional presentations with worsening symptoms and lesion accumulation, he was ultimately successfully treated with rituximab for his condition.

Indexed as

Brain DiseasesDemyelinating DiseasesOphthalmoplegiaAdolescentAtaxiaHumansMaleRituximabRituximab

Identifiers

PMID38181318

DOI10.1212/NXI.0000000000200193

PMCPMC11078149

OpenAlexW4390629214

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.