Evidence map›Paper›PMID 38180898›Full record

ArticleJournal of the National Cancer Institute2024

Sociodemographic inequities in the burden of carcinogenic industrial air emissions in the United States.

Jessica M Madrigal, Abigail Flory, Jared A Fisher, Elizabeth Sharp, Barry I Graubard, Mary H Ward, Rena R Jones

Open access · hybridAbstract read
In one paragraph

Article in Journal of the National Cancer Institute, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
36.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. The upside and challenge of getting it wrong.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Potential Exposure to Environmental Toxic Emissions and Increased Cancer Risk in Puerto Rico.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  10. Air Pollutants in Puerto Rico: Key Pollutants and Carcinogenic Properties.International journal of environmental research and public health · 2025
    Review
  11. Review
  12. Article
  13. Identifying differences in U.S. exposure to ubiquitous carcinogens.International journal of hygiene and environmental health · 2025
    Article
  14. Article
  15. Lung Cancer and the Environment.American journal of respiratory and critical care medicine · 2025
    Article
  16. Carcinogenic Industrial Air Emissions and Lung Cancer Risk in a Cohort of 440,000 Americans.American journal of respiratory and critical care medicine · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jessica M MadrigalOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA.ORCID 0000-0001-5303-5109
Abigail FloryWestat Inc, Rockville, MD, USA.
Jared A FisherOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA.
Elizabeth SharpOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA.
Barry I GraubardBiostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA.ORCID 0000-0002-6787-1105
Mary H WardOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA.
Rena R JonesOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA.
National Institutes of Health · USWestat (United States) · US

Funding

Cancer Risk and Environmental ExposuresZIACP010125 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI PURDUE, MARK · 2009 to 2025
$41.3M
Occupational and Environmental Determinants of Cancer among Women and MinoritiesZIACP010123 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI HOFMANN, JONATHAN · 2009 to 2025
$8.3M
Intramural NIH HHS ZIA CP010125
6 · The paper itself

Abstract

backgroundIndustrial facilities are not located uniformly across communities in the United States, but how the burden of exposure to carcinogenic air emissions may vary across population characteristics is unclear. We evaluated differences in carcinogenic industrial pollution among major sociodemographic groups in the United States and Puerto Rico.

methodsWe evaluated cross-sectional associations of population characteristics including race and ethnicity, educational attainment, and poverty at the census tract level with point-source industrial emissions of 21 known human carcinogens using regulatory data from the US Environmental Protection Agency. Odds ratios and 95% confidence intervals comparing the highest emissions (tertile or quintile) to the referent group (zero emissions [ie, nonexposed]) for all sociodemographic characteristics were estimated using multinomial, population density-adjusted logistic regression models.

resultsIn 2018, approximately 7.4 million people lived in census tracts with nearly 12 million pounds of carcinogenic air releases. The odds of tracts having the greatest burden of benzene, 1,3-butadiene, ethylene oxide, formaldehyde, trichloroethylene, and nickel emissions compared with nonexposed were 10%-20% higher for African American populations, whereas White populations were up to 18% less likely to live in tracts with the highest emissions. Among Hispanic and Latino populations, odds were 16%-21% higher for benzene, 1,3-butadiene, and ethylene oxide. Populations experiencing poverty or with less than high school education were associated with up to 51% higher burden, irrespective of race and ethnicity.

conclusionsCarcinogenic industrial emissions disproportionately impact African American and Hispanic and Latino populations and people with limited education or experiencing poverty thus representing a source of pollution that may contribute to observed cancer disparities.

Indexed as

Air PollutantsAir PollutionBenzeneButadienesCarcinogensCross-Sectional StudiesEnvironmental ExposureFormaldehydeHumansIndustryNickelPuerto RicoSociodemographic FactorsSocioeconomic FactorsUnited States1,3-butadieneAir PollutantsBenzeneButadienesCarcinogensFormaldehydeNickel

Identifiers

PMID38180898
PMCPMC11077313
OpenAlexW4390619562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.