Evidence map›Paper›PMID 38180737›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2024

New HIV Infections Among Key Populations and Their Partners in 2010 and 2022, by World Region: A Multisources Estimation.

Eline L Korenromp, Keith Sabin, John Stover, Tim Brown, Leigh F Johnson, Rowan Martin-Hughes, Debra Ten Brink, Yu Teng, Oliver Stevens, Romain Silhol and 5 more

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Circumcision for HIV Prevention in Men Who Have Sex With Men: An Updated Meta-Analysis.Journal of acquired immune deficiency syndromes (1999) · 2026
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Eline L KorenrompData for Impact Department, The Joint United Nations Program on HIV/AIDS (UNAIDS), Geneva, Switzerland.ORCID 0000-0002-5301-8461
Keith SabinData for Impact Department, The Joint United Nations Program on HIV/AIDS (UNAIDS), Geneva, Switzerland.
John StoverCenter for Modeling, Planning and Policy Analysis, Avenir Health, Glastonbury, CT.
Tim BrownResearch Program, East-West Center, Honolulu, HI.
Leigh F JohnsonCentre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa.
Rowan Martin-HughesMacfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Australia.
Debra Ten BrinkMacfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Australia.
Yu TengCenter for Modeling, Planning and Policy Analysis, Avenir Health, Glastonbury, CT.
Oliver StevensMRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, United Kingdom.
Romain SilholMRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, United Kingdom.
Sonia Arias-GarciaData for Impact Department, The Joint United Nations Program on HIV/AIDS (UNAIDS), Geneva, Switzerland.
Joshua KimaniPartners for Health and Development in Africa, Nairobi, Kenya.
Robert GlaubiusCenter for Modeling, Planning and Policy Analysis, Avenir Health, Glastonbury, CT.
Peter VickermanPopulation Health Sciences, University of Bristol, Bristol, United Kingdom.
Mary MahyData for Impact Department, The Joint United Nations Program on HIV/AIDS (UNAIDS), Geneva, Switzerland.

Funding

SDMC: HPTN 084 Pregnancy SupplementUM1AI068617 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Elizabeth Renata Brown, Deborah J Donnell · 2011 to 2026
$204.9M
NIAID NIH HHS UM1 AI068617Wellcome Trust
6 · The paper itself

Abstract

backgroundPreviously, The Joint United Nations Programme on HIV/AIDS estimated proportions of adult new HIV infections among key populations (KPs) in the last calendar year, globally and in 8 regions. We refined and updated these, for 2010 and 2022, using country-level trend models informed by national data.

methodsInfections among 15-49 year olds were estimated for sex workers (SWs), male clients of female SW, men who have sex with men (MSM), people who inject drugs (PWID), transgender women (TGW), and non-KP sex partners of these groups. Transmission models used were Goals (71 countries), AIDS Epidemic Model (13 Asian countries), Optima (9 European and Central Asian countries), and Thembisa (South Africa). Statistical Estimation and Projection Package fits were used for 15 countries. For 40 countries, new infections in 1 or more KPs were approximated from first-time diagnoses by the mode of transmission. Infection proportions among nonclient partners came from Goals, Optima, AIDS Epidemic Model, and Thembisa. For remaining countries and groups not represented in models, median proportions by KP were extrapolated from countries modeled within the same region.

resultsAcross 172 countries, estimated proportions of new adult infections in 2010 and 2022 were both 7.7% for SW, 11% and 20% for MSM, 0.72% and 1.1% for TGW, 6.8% and 8.0% for PWID, 12% and 10% for clients, and 5.3% and 8.2% for nonclient partners. In sub-Saharan Africa, proportions of new HIV infections decreased among SW, clients, and non-KP partners but increased for PWID; elsewhere these groups' 2010-to-2022 differences were opposite. For MSM and TGW, the proportions increased across all regions.

conclusionsKPs continue to have disproportionately high HIV incidence.

Indexed as

Acquired Immunodeficiency SyndromeHIV InfectionsSexual and Gender MinoritiesSubstance Abuse, IntravenousAdultFemaleHomosexuality, MaleHumansMale

Identifiers

PMID38180737
PMCPMC10769164

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.