Evidence map›Paper›PMID 38180722›Full record

SynthesisCurrent gastroenterology reports2024

Managing IBD Patients with Concomitant HIV Infection - a Systematic Review.

Hugo Sousa, Joana Barroso, Raquel Tavares, Joana Torres

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Current gastroenterology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hugo SousaFaculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
Joana BarrosoFaculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
Raquel TavaresFaculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
Joana TorresFaculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal. joanatorres00@gmail.com.
University of Lisbon · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewInflammatory Bowel Disease (IBD) is a chronic GI inflammatory condition induced by a dysregulated immune system activation, whereas HIV infection causes depletion of the immune system, inducing immunosuppression. Given the increasing incidence of IBD across the globe, including in developing countries, the co-prevalence of both conditions is expected to increase. Herein, we systematically review the data describing disease course when both pathologies co-exist. RECENT

findingsOverall, the co-prevalence of IBD and HIV is around 0.1 to 2%. While IBD does not seem to affect HIV course, the opposite is controversial, as some studies report milder IBD phenotype, with fewer disease relapses especially when CD4 + counts are lower than 200 cells/µL. Despite growing evidence to support the safety of the use of immunosuppressants and biologics in IBD-HIV infected patients, these classes of drugs are used in less than 50% of patients, as compared to non-HIV infected IBD patients. There is a need for more studies on disease course and safety of IBD medications in the setting of IBD.

Indexed as

Colitis, UlcerativeHIV InfectionsInflammatory Bowel DiseasesHumansImmunosuppression TherapyImmunosuppressive AgentsImmunosuppressive AgentsCrohn’s DiseaseHuman Immunodeficiency VirusInflammatory Bowel DiseaseManagementUlcerative Colitis

Identifiers

PMID38180722
OpenAlexW4390608365

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.