Evidence map›Paper›PMID 38180586›Full record

ArticleThe protein journal2024

Heterologous Production of Antimicrobial Peptides: Notes to Consider.

Masoumeh Kordi, Parnian Ghaedi Talkhounche, Helia Vahedi, Naser Farrokhi, Maryam Tabarzad

Abstract read
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In one paragraph

Article in The protein journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Discovery of Novel Genes Encoding Antimicrobial Peptides from theInternational journal of molecular sciences · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Exploring the seas for cancer cures: the promise of marine-derived bioactive peptide.International journal of biochemistry and molecular biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Masoumeh KordiDepartment of Cell & Molecular Biology, Faculty of Life Sciences & Biotechnology, Shahid Beheshti University, Tehran, Iran.ORCID http://orcid.org/0000-0002-9123-3103
Parnian Ghaedi TalkhouncheDepartment of Cell & Molecular Biology, Faculty of Life Sciences & Biotechnology, Shahid Beheshti University, Tehran, Iran.
Helia VahediDepartment of Cell & Molecular Biology, Faculty of Life Sciences & Biotechnology, Shahid Beheshti University, Tehran, Iran.
Naser FarrokhiDepartment of Cell & Molecular Biology, Faculty of Life Sciences & Biotechnology, Shahid Beheshti University, Tehran, Iran. n_farrokhi@sbu.ac.ir.ORCID http://orcid.org/0000-0002-4195-1756
Maryam TabarzadProtein Technology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. m_tabarzad@sbmu.ac.ir.ORCID http://orcid.org/0000-0001-9923-0639
Shahid Beheshti University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heavy and irresponsible use of antibiotics in the last century has put selection pressure on the microbes to evolve even faster and develop more resilient strains. In the confrontation with such sometimes called "superbugs", the search for new sources of biochemical antibiotics seems to have reached the limit. In the last two decades, bioactive antimicrobial peptides (AMPs), which are polypeptide chains with less than 100 amino acids, have attracted the attention of many in the control of microbial pathogens, more than the other types of antibiotics. AMPs are groups of components involved in the immune response of many living organisms, and have come to light as new frontiers in fighting with microbes. AMPs are generally produced in minute amounts within organisms; therefore, to address the market, they have to be either produced on a large scale through recombinant DNA technology or to be synthesized via chemical methods. Here, heterologous expression of AMPs within bacterial, fungal, yeast, plants, and insect cells, and points that need to be considered towards their industrialization will be reviewed.

Indexed as

Antimicrobial PeptidesAnimalsBacteriaFungiInsectaPlantsRecombinant ProteinsAntimicrobial PeptidesRecombinant ProteinsChemical synthesisFusion peptideHeterologous peptide expressionRecombinant peptide isolation

Identifiers

PMID38180586
OpenAlexW4390617917

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.