Evidence map›Paper›PMID 38180556›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2024

Sesamol as a potent anticancer compound: from chemistry to cellular interactions.

Ajay Kumar, Payal Bajaj, Brahmjot Singh, Kapil Paul, Pooja Sharma, Sukanya Mehra, Robin, Pardeep Kaur, Shivam Jasrotia, Parveen Kumar and 3 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
4.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Structural analysis of ITS 1 gene ofFrontiers in cellular and infection microbiology · 2026
    Article
  2. Sesame Seeds: A Nutrient-Rich Superfood.Foods (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 2 countries.

Ajay KumarUniversity Center for Research & Development (UCRD), Biotechnology Engineering & Food Technology, Chandigarh University, Gharuan, Mohali, 140413, Punjab, India. kumar.ajay1250@gmail.com.
Payal BajajAdvanced Eye Center, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.
Brahmjot SinghDepartment of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, 143005, Punjab, India.
Kapil PaulKanya Maha Vidyalaya, Jalandhar, 144004, Punjab, India.
Pooja SharmaDepartment of Chemistry, Guru Nanak Dev University, Amritsar, 143005, Punjab, India.
Sukanya MehraP.G. Department of Science, Khalsa College For Women, Amritsar, 143001, Punjab, India.
RobinRegional Water Testing Laboratory, Department of Water Supply and Sanitation, Agilent Technologies India Pvt. Ltd., Amritsar, Punjab, India.
Pardeep KaurPost Graduate Department of Botany, Khalsa College, Amritsar, Punjab, India.
Shivam JasrotiaDepartment of Biosciences, University Institute of Biotechnology, Chandigarh University, Mohali, Punjab, 140413, India.
Parveen KumarDepartment of Chemistry, Chandigarh University, Gharuan, Mohali, 140413, Punjab, India.
RajatPunjab Biotechnology Incubator (PBTI), Phase VIII, Mohali, 160071, India.
Vipourpreet SinghCoast Mountain College, Prince Rupert, British Columbia, V8J3S8, Canada.
Hardeep Singh TuliDepartment of Bio-Sciences and Technology, Maharishi Markandeshwar Engineering College, Maharishi Markandeshwar (Deemed to Be University), Mullana, Ambala, 133207, India.
Chandigarh University · INAgilent Technologies (India) · INGovernment Medical College, Amritsar · INGuru Nanak Dev University · INCoast Mountain College · CAKanya Maha Vidyalaya · INMaharishi Markandeshwar University, Mullana · INPost Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sesamol (SM), a well-known component isolated from sesame seeds (Sesamum indicum), used in traditional medicines in treating numerous ailments. However, numerous molecular investigations revealed the various mechanisms behind its activity, emphasizing its antiproliferative, anti-inflammatory, and apoptosis-inducing properties, preventing cancer cell spread to distant organs. In several cells derived from various malignant tissues, SM-regulated signal transduction pathways and cellular targets have been identified. This review paper comprehensively describes the anticancer properties of SM and SM-viable anticancer drugs. Additionally, the interactions of this natural substance with standard anticancer drugs are examined, and the benefits of using nanotechnology in SM applications are explored. This makes SM a prime example of how ethnopharmacological knowledge can be applied to the development of contemporary drugs.

Indexed as

BenzodioxolesPhenolsAnimalsAntineoplastic AgentsAntineoplastic Agents, PhytogenicApoptosisHumansNeoplasmsAntineoplastic AgentsAntineoplastic Agents, PhytogenicBenzodioxolesPhenolssesamolAnticancerAnti-inflammatoryAntiproliferativeApoptosisEthnopharmacologicalNanotechnologySesamol

Identifiers

PMID38180556
OpenAlexW4390609231

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.