Evidence map›Paper›PMID 38180534›Full record

ReviewDiscover nano2024

Prodrug-based nanomedicines for rheumatoid arthritis.

Pei Li, Cong Wang, Hongjie Huo, Chunyun Xu, Huijun Sun, Xinyu Wang, Li Wang, Lei Li

Open access · diamondAbstract readReview
In one paragraph

Review in Discover nano, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Pei Li *College of Pharmacy, Dalian Medical University, Dalian, China.
Cong Wang *College of Pharmacy, Dalian Medical University, Dalian, China.
Hongjie HuoCollege of Pharmacy, Dalian Medical University, Dalian, China.
Chunyun XuCollege of Pharmacy, Dalian Medical University, Dalian, China.
Huijun SunCollege of Pharmacy, Dalian Medical University, Dalian, China.
Xinyu WangCollege of Pharmacy, Dalian Medical University, Dalian, China.
Li WangCollege of Pharmacy, Dalian Medical University, Dalian, China. wldl2007@126.com.
Lei LiCollege of Pharmacy, Dalian Medical University, Dalian, China. ll_wht@163.com.
Dalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most antirheumatic drugs with high toxicity exhibit a narrow therapeutic window due to their nonspecific distribution in the body, leading to undesirable side effects and reduced patient compliance. To in response to these challenges, prodrug-based nanoparticulate drug delivery systems (PNDDS), which combines prodrug strategy and nanotechnology into a single system, resulting their many advantages, including stability for prodrug structure, the higher drug loading capacity of the system, improving the target activity and bioavailability, and reducing their untoward effects. PNDDS have gained attention as a method for relieving arthralgia syndrome of rheumatoid arthritis in recent years. This article systematically reviews prodrug-based nanocarriers for rheumatism treatment, including Nano systems based on prodrug-encapsulated nanomedicines and conjugate-based nanomedicines. It provides a new direction for the clinical treatment of rheumatoid arthritis.

Indexed as

Drug delivery systemsProdrug-based nanoparticulateRheumatoid arthritisTargeted therapy

Identifiers

PMID38180534
PMCPMC10769998
OpenAlexW4390615261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.