Evidence map›Paper›PMID 38179626›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2024

Relative vaccine effectiveness against COVID-19 hospitalisation in persons aged ≥ 65 years: results from a VEBIS network, Europe, October 2021 to July 2023.

Mario Fontán-Vela, Esther Kissling, Nathalie Nicolay, Toon Braeye, Izaak Van Evercooren, Christian Holm Hansen, Hanne-Dorthe Emborg, Massimo Fabiani, Alberto Mateo-Urdiales, Ala'a AlKerwi and 14 more

Open access · diamondAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 12 institutions in 10 countries.

Mario Fontán-VelaNational Centre of Epidemiology, Carlos III National Health Institute (ISCIII), Madrid, Spain.
Esther KisslingEpiconcept, Paris, France.
Nathalie NicolayVaccine Preventable Diseases and Immunisation, European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Toon BraeyeSciensano, Elsene, Belgium.
Izaak Van EvercoorenSciensano, Elsene, Belgium.
Christian Holm HansenDepartment of Infectious Disease Epidemiology and Prevention, Statens Serum Institut (SSI), Copenhagen, Denmark.
Hanne-Dorthe EmborgDepartment of Infectious Disease Epidemiology and Prevention, Statens Serum Institut (SSI), Copenhagen, Denmark.
Massimo FabianiInfectious Diseases Department, Istituto Superiore di Sanità, Rome, Italy.
Alberto Mateo-UrdialesInfectious Diseases Department, Istituto Superiore di Sanità, Rome, Italy.
Ala'a AlKerwiMinistry of Health, Directorate of Health, Service epidemiology and statistics, Luxembourg.
Susanne SchmitzMinistry of Health, Directorate of Health, Service epidemiology and statistics, Luxembourg.
Jesús CastillaCIBER Epidemiología y Salud Pública (CIBERESP), Spain.
Iván Martínez-BazCIBER Epidemiología y Salud Pública (CIBERESP), Spain.
Brechje de GierCenter for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
Susan HahnéCenter for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
Hinta MeijerinkNorwegian Institute of Public Health (NIPH), Oslo, Norway.
Jostein StarrfeltNorwegian Institute of Public Health (NIPH), Oslo, Norway.
Baltazar NunesDepartamento de Epidemiologia, Instituto Nacional de Saúde Doutor Ricardo Jorge, Departamento de Epidemiologia, Lisboa, Portugal.
Constantino CaetanoDepartamento de Epidemiologia, Instituto Nacional de Saúde Doutor Ricardo Jorge, Departamento de Epidemiologia, Lisboa, Portugal.
Tarik DerroughVaccine Preventable Diseases and Immunisation, European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Anthony NardoneEpiconcept, Paris, France.
Susana MongeNational Centre of Epidemiology, Carlos III National Health Institute (ISCIII), Madrid, Spain.
VEBIS-Lot4 working groupThe members of the VEBIS-Lot4 working group are listed under Collaborators.
VEBIS-Lot 4 working group
European Centre for Disease Prevention and Control · SEInstituto de Salud Pública de Navarra · ESIstituto Superiore di Sanità · ITLuxembourg Institute of Health · LUNational Institute for Public Health and the Environment · NLNational Institute of Health Dr. Ricardo Jorge · PTNorwegian Institute of Public Health · NOSciensano (Belgium) · BEStatens Serum Institut · DKCollaborative Group (United States) · USInstituto de Salud Carlos III · ESUniversidad de Alcalá · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To monitor relative vaccine effectiveness (rVE) against COVID-19-related hospitalisation of the first, second and third COVID-19 booster (vs complete primary vaccination), we performed monthly Cox regression models using retrospective cohorts constructed from electronic health registries in eight European countries, October 2021-July 2023. Within 12 weeks of administration, each booster showed high rVE (≥ 70% for second and third boosters). However, as of July 2023, most of the relative benefit has waned, particularly in persons ≥ 80-years-old, while some protection remained in 65-79-year-olds.

Indexed as

COVID-19Aged, 80 and overEuropeHospitalizationHumansRetrospective StudiesVaccine Efficacycohort designCOVID-19electronic health recordshospitalisationmulti-country studySARS-CoV-2vaccine effectiveness

Identifiers

PMID38179626
PMCPMC10905661
OpenAlexW4390608521

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.