Evidence map›Paper›PMID 38179189›Full record

ArticleJournal of osteoporosis2023

Quantitative MR Analysis of Changes in the Radius Bone Marrow in Osteoporosis.

Tamar K De-Levie, Yael S Schiffenbauer, Ido Druckmann, Vanessa Rouach, Naftali Stern, Itzhak Binderman, Uri Nevo

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of osteoporosis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03742362 (MRI Study of the Distal Radius Bone Marrow Fat Fraction in Osteoporotic and Healthy Women), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 75% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03742362 nacompletednot on this map

MRI Study of the Distal Radius Bone Marrow Fat Fraction in Osteoporotic and Healthy Women

TypeinterventionalSponsorUri NevoRan2019 to 2019Enrolled26ConditionsOsteoporosis, PostmenopausalArmsMRI scans of distal radius
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tamar K De-LevieDepartment of Biomedical Engineering, Tel Aviv University, Tel Aviv, Israel.ORCID https://orcid.org/0000-0001-6679-0760
Yael S SchiffenbauerDepartment of Biomedical Engineering, Tel Aviv University, Tel Aviv, Israel.
Ido DruckmannSkeletal Imaging Division, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Vanessa RouachInstitute of Endocrinology, Metabolism and Hypertension, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Naftali SternFaculty of Medicine, Tel Aviv University, Tel Aviv, Israel.ORCID https://orcid.org/0000-0002-5123-3176
Itzhak BindermanDepartment of Oral Biology, School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel.ORCID https://orcid.org/0000-0002-7352-0352
Uri NevoDepartment of Biomedical Engineering, Tel Aviv University, Tel Aviv, Israel.ORCID https://orcid.org/0000-0002-9343-6609
Tel Aviv University · ILTel Aviv Sourasky Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This pilot study aimed to explore the feasibility of scanning the human distal radius bone marrow in vivo to detect osteoporosis-related changes using magnetic resonance and evaluate whether the radius may serve as an accessible probing site for osteoporosis. This may lead in the future to the use of affordable means such as low-field MRI scanners for the monitoring of disease progression. Methods: A clinical trial was performed using a 3T MR scanner, including 26 women assigned into three study groups: healthy-premenopausal ( Results: The osteoporotic group exhibited higher fat content than the other two groups and lower T2 values than the healthy-premenopausal group. Conclusions: Osteoporosis-related changes in the composition of the distal radius bone marrow may be detected in vivo using MRI protocols. The scanning protocols chosen here can later be repeated using low-field MRI scanners, thus offering the potential for early detection and treatment monitoring, using an accessible, affordable means that may be applied in small clinics. This trial is registered with MOH_2018-05-23_002247, NCT03742362.

Identifiers

PMID38179189
PMCPMC10764646
OpenAlexW4390263142

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.