Evidence map›Paper›PMID 38179041›Full record

ArticleFrontiers in immunology2023

The mosquito effect: regulatory and effector T cells acquire cytoplasmic material from tumor cells through intercellular transfer.

Kaito A Hioki, Daniel J Ryan, Iris Thesmar, Adam C Lynch, Leonid A Pobezinsky, Elena L Pobezinskaya

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kaito A HiokiDepartment of Veterinary and Animal Science, University of Massachusetts, Amherst, MA, United States.
Daniel J RyanDepartment of Veterinary and Animal Science, University of Massachusetts, Amherst, MA, United States.
Iris ThesmarDepartment of Veterinary and Animal Science, University of Massachusetts, Amherst, MA, United States.
Adam C LynchDepartment of Veterinary and Animal Science, University of Massachusetts, Amherst, MA, United States.
Leonid A PobezinskyDepartment of Veterinary and Animal Science, University of Massachusetts, Amherst, MA, United States.
Elena L PobezinskayaDepartment of Veterinary and Animal Science, University of Massachusetts, Amherst, MA, United States.
University of Massachusetts Amherst · US

Funding

Biotechnology Training Program in Applied Life SciencesT32GM135096 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Jeanne Ann Hardy, Ashish A. Kulkarni · 2020 to 2026
$3.9M
Defining post-transcriptional mechanisms that control CD8 T cell longevity, proliferation and differentiationR01AI146188 · NIAID · UNIVERSITY OF MASSACHUSETTS AMHERST · PI POBEZINSKIY, LEONID · 2020 to 2024
$2.7M
Defining the role of let-7 miRNAs in the differentiation of exhausted and memory T cellsR21AI133041 · NIAID · UNIVERSITY OF MASSACHUSETTS AMHERST · PI POBEZINSKIY, LEONID · 2018 to 2019
$444k
NIAID NIH HHS R01 AI146188NIAID NIH HHS R21 AI133041NIGMS NIH HHS T32 GM135096
6 · The paper itself

Abstract

The phenomenon of intercellular transfer of cellular material, including membranes, cytoplasm, and even organelles, has been observed for decades. The functional impact and molecular mechanisms of such transfer in the immune system remain largely elusive due to the absence of a robust

Indexed as

CD8-Positive T-LymphocytesLymphocytes, Tumor-InfiltratingAnimalsCytoplasmCytosolDisease Models, AnimalMiceCD8 T cellscytoplasmexhaustionintercellular transferTregstumor

Identifiers

PMID38179041
PMCPMC10765531
OpenAlexW4390013037

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.