Evidence map›Paper›PMID 38179003›Full record

ArticleToxicology research2024

Selenium and zinc supplementation mitigates metals-(loids) mixture- mediated cardiopulmonary toxicity via attenuation of antioxidant, anti-inflammatory and antiapoptotic mechanisms in female Sprague Dawley rats.

Mfoniso Antia, Anthonet N Ezejiofor, Chinna N Orish, Ana Cirovic, Aleksandar Cirovic, Orish E Orisakwe

Open access · greenAbstract read
In one paragraph

Article in Toxicology research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Protective Effect of PEG-EDTA and Its Zinc(II) Complex on Human Cells.International journal of molecular sciences · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Mfoniso AntiaAfrican Centre of Excellence for Public Health and Toxicological Research (ACE-PUTOR), University of Port Harcourt, PMB, East West Road, Choba, Port Harcourt, Rivers State, Choba 5323, Nigeria.
Anthonet N EzejioforAfrican Centre of Excellence for Public Health and Toxicological Research (ACE-PUTOR), University of Port Harcourt, PMB, East West Road, Choba, Port Harcourt, Rivers State, Choba 5323, Nigeria.ORCID https://orcid.org/0000-0002-3948-399X
Chinna N OrishDepartment of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Port Harcourt, PMB, East West Road, Choba, Port Harcourt, Rivers State, Choba 5323, Nigeria.ORCID https://orcid.org/0000-0001-5627-6055
Ana CirovicFaculty of Medicine, The Institute of Anatomy, University of Belgrade, East West Road, Choba, Port Harcourt, Rivers State Belgrade, Serbia.ORCID https://orcid.org/0009-0004-9085-5308
Aleksandar CirovicFaculty of Medicine, The Institute of Anatomy, University of Belgrade, East West Road, Choba, Port Harcourt, Rivers State Belgrade, Serbia.ORCID https://orcid.org/0000-0001-6010-9559
Orish E OrisakweAfrican Centre of Excellence for Public Health and Toxicological Research (ACE-PUTOR), University of Port Harcourt, PMB, East West Road, Choba, Port Harcourt, Rivers State, Choba 5323, Nigeria.ORCID https://orcid.org/0000-0002-5806-9858
University of Port Harcourt · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the cardiopulmonary protective effects of essential elements (Zn and Se) against heavy metals mixture (HMM) exposure. Twenty five female Sprague Dawley albino rats, divided in to five groups: controls were orally treated only with distilled water; next, group 2 was exposed to HMM with the following concentrations: 20 mg/kg of Pb body weight, 0.40 mg/kg of Hg, 0.56 mg/kg of Mn, and 35 mg/kg of Al. Groups 3, 4 and 5 were exposed to HMM and co-treated with zinc chloride (ZnCl

Indexed as

essential trace elementsheartheavy metalslungsmetalloidsoxido-inflammatory

Identifiers

PMID38179003
PMCPMC10762678
OpenAlexW4389575314

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.