Evidence map›Paper›PMID 38178918›Full record

ReviewMolecular therapy. Nucleic acids2024

A contemporary review of snoRNAs in cardiovascular health: RNA modification and beyond.

Noah Peter Jagielski, Amit Kumar Rai, K Shanmugha Rajan, Vatsal Mangal, Venkata Naga Srikanth Garikipati

Open access · goldAbstract readReview
In one paragraph

Review in Molecular therapy. Nucleic acids, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Small non-coding RNA YF1: A new dawn in heart transplantation.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Noah Peter JagielskiAging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
Amit Kumar RaiAging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
K Shanmugha RajanDepartment of Chemical and Structural Biology, Weizmann Institute, Rehovot 76100 001, Israel.
Vatsal MangalAging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
Venkata Naga Srikanth GarikipatiAging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
Temple University · USWeizmann Institute of Science · IL

Funding

Role of small RNAs in ischemic tissue repairR01HL164794 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI Venkata Naga Srikanth Garikipati · 2023 to 2026
$2.2M
NHLBI NIH HHS R01 HL164794
6 · The paper itself

Abstract

As cardiovascular diseases continue to be the leading cause of death worldwide, groundbreaking research is being conducted to mitigate their effects. This review looks into the potential of small nucleolar RNAs (snoRNAs) and the opportunity to use these molecular agents as therapeutic biomarkers for cardiovascular issues specific to the heart. Through an investigation of snoRNA biogenesis, functionality, and roles in cardiovascular diseases, this review relates our past and present knowledge of snoRNAs to the current scientific literature. Considering the initial discovery of snoRNAs and the studies thereafter analyzing the roles of snoRNAs in disease, we look forward to uncovering many other noncanonical functions that could lead researchers closer to finding preventive and curative solutions for cardiovascular diseases.

Indexed as

cardiovascular diseasesC/D box snoRNAH/ACA box snoRNAMT: Noncoding RNAsnoncoding RNAsRNA modificationscaRNA

Identifiers

PMID38178918
PMCPMC10765057
OpenAlexW4389328435

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.