Evidence map›Paper›PMID 38178208›Full record

ArticleAdvances in rheumatology (London, England)2024

Systemic and local antiinflammatory effect of magnesium chloride in experimental arthritis.

Ana Carolina Matias Dinelly Pinto, Rodolfo de Melo Nunes, Waleska Vidal de Freitas Carvalho, Virgínia Claudia Carneiro Girão, Francisco Airton Castro Rocha

Open access · diamondAbstract read
In one paragraph

Article in Advances in rheumatology (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ana Carolina Matias Dinelly PintoPrograma de Pós-Graduação em Biotecnologia em Saúde Humana e Animal da Universidade Estadual do Ceará, Fortaleza - Ceará, Brazil.
Rodolfo de Melo NunesDepartamento de Medicina Interna da Faculdade de Medicina da Universidade Federal do Ceará, Fortaleza - Ceará, Brazil.
Waleska Vidal de Freitas CarvalhoPrograma de Pós-Graduação em Biotecnologia em Saúde Humana e Animal da Universidade Estadual do Ceará, Fortaleza - Ceará, Brazil.
Virgínia Claudia Carneiro GirãoDepartamento de Morfologia da Faculdade de Medicina da Universidade Federal do Ceará, Fortaleza - Ceará, Brazil.
Francisco Airton Castro RochaDepartamento de Medicina Interna da Faculdade de Medicina da Universidade Federal do Ceará, Fortaleza - Ceará, Brazil. arocha@ufc.br.ORCID 0000-0003-4370-3294
Universidade Federal do Ceará · BRUniversidade Estadual do Ceará · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 313860/2021-1; 403767/2021-0
6 · The paper itself

Abstract

objectiveDespite some knowledge gaps in scientific evidence, MgCl

methodsMice received 0.1 mg/25µL Zymosan (Zy) or saline into the knees. Joint pain was evaluated using von Frey test; cell influx, and interleukin (IL)-1 level were assessed in joint lavage at 6 h. Synovia were excised for histopathology and analysis of immunoexpression of nuclear factor kappa B (NFκB) and tumor necrosis factor (TNF)-α. Groups (n = 6/group) received either 90 mg/kg MgCl

resultsMgCl

conclusionMgCl

Indexed as

Arthritis, ExperimentalAnimalsAnti-Inflammatory AgentsCytokinesHumansInterleukin-1Magnesium ChlorideMicePainRatsRats, WistarTumor Necrosis Factor-alphaAnti-Inflammatory AgentsCytokinesInterleukin-1Magnesium ChlorideTumor Necrosis Factor-alphaArthritisInflammationMagnesiumPainZymosan

Identifiers

PMID38178208
PMCPMC13488771
OpenAlexW4390590034

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.