Evidence map›Paper›PMID 38178173›Full record

Trial reportBMC health services research2024

Health care providers acceptance of default prescribing of TB preventive treatment for people living with HIV in Malawi: a qualitative study.

L M De Groot, K Shearer, C Sambani, E Kaonga, R Nyirenda, K Mbendera, J E Golub, C J Hoffmann, C Mulder

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC health services research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
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  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

L M De GrootTB Elimination and Health System Innovations - KNCV Tuberculosis Foundation, The Hague, The Netherlands.
K ShearerCenter for Tuberculosis Research, John Hopkins University, Baltimore, MD, USA.
C SambaniDepartment of Research, Ministry of Health, Lilongwe, Malawi.
E KaongaKNCV Tuberculosis Foundation, Lilongwe, Malawi.
R NyirendaDepartment of HIV and AIDS, Ministry of Health, Lilongwe, Malawi.
K MbenderaNational Tuberculosis and Leprosy Elimination Program, Ministry of Health, Lilongwe, Malawi.
J E GolubCenter for Tuberculosis Research, John Hopkins University, Baltimore, MD, USA.
C J HoffmannCenter for Tuberculosis Research, John Hopkins University, Baltimore, MD, USA.
C MulderTB Elimination and Health System Innovations - KNCV Tuberculosis Foundation, The Hague, The Netherlands. christiaan.mulder@kncvtbc.org.
Johns Hopkins University · USMinistry of Health · MWAmsterdam Institute for Global Health and Development · NLTuBerculosis Vaccine Initiative · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTuberculosis (TB) preventive treatment (TPT) substantially reduces the risk of developing active TB for people living with HIV (PLHIV). We utilized a novel implementation strategy based on choice architecture (CAT) which makes TPT prescribing the default option. Through CAT, health care workers (HCWs) need to "opt-out" when choosing not to prescribe TPT to PLHIV. We assessed the prospective, concurrent, and retrospective acceptability of TPT prescribing among HCWs in Malawi who worked in clinics participating in a cluster randomized trial of the CAT intervention.

methods28 in-depth semi-structured interviews were conducted with HCWs from control (standard prescribing approach) and intervention (CAT approach) clinics. The CAT approach was facilitated in intervention clinics using a default prescribing module built into the point-of-care HIV Electronic Medical Record (EMR) system. An interview guide for the qualitative CAT assessment was developed based on the theoretical framework of acceptability and on the normalization process theory. Thematic analysis was used to code the data, using NVivo 12 software.

resultsWe identified eight themes belonging to the three chronological constructs of acceptability. HCWs expressed no tension for changing the standard approach to TPT prescribing (prospective acceptability); however, those exposed to CAT described several advantages, including that it served as a reminder to prescribe TPT and routinized TPT prescribing (concurrent acceptability). Some felt that CAT may reduce HCW´s autonomy and might lead to inappropriate TPT prescribing (retrospective acceptability).

conclusionsThe default prescribing module for TPT has now been incorporated into the point-of-care EMR system nationally in Malawi. This seems to fit the acceptability of the HCWs. Moving forward, it is important to train HCWs on how the EMR can be leveraged to determine who is eligible for TPT and who is not, while acknowledging the autonomy of HCWs.

Indexed as

HIV InfectionsTuberculosisHealth PersonnelHumansMalawiProspective StudiesRetrospective StudiesAcceptabilityChoice architectureHealth care providersPeople living with HIVPreventive treatmentTuberculosis

Identifiers

PMID38178173
PMCPMC10768226
OpenAlexW4390580623

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.