Evidence map›Paper›PMID 38178147›Full record

ArticleRespiratory research2024

Risk factors for prolonged mechanical ventilation in critically ill patients with influenza-related acute respiratory distress syndrome.

Pai-Chi Hsu, Yi-Tsung Lin, Kuo-Chin Kao, Chung-Kan Peng, Chau-Chyun Sheu, Shinn-Jye Liang, Ming-Cheng Chan, Hao-Chien Wang, Yu-Mu Chen, Wei-Chih Chen and 2 more

Open access · goldAbstract read
In one paragraph

Article in Respiratory research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Risk factors for prolonged mechanical ventilation in critically ill patients with ischemic stroke.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 11 institutions in 1 country.

Pai-Chi HsuInstitute of Emergency and Critical Care Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Yi-Tsung LinInstitute of Emergency and Critical Care Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Kuo-Chin KaoDepartment of Thoracic Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Chung-Kan PengDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Tri-Service General Hospital, Taipei, Taiwan.
Chau-Chyun SheuDivision of Pulmonary and Critical Care Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Shinn-Jye LiangDivision of Pulmonary and Critical Care, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.
Ming-Cheng ChanDepartment of Critical Care Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
Hao-Chien WangDivision of Chest Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Yu-Mu ChenDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Wei-Chih Chen *Institute of Emergency and Critical Care Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Kuang-Yao Yang *Institute of Emergency and Critical Care Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan. kyyang@vghtpe.gov.tw.
TSIRC (Taiwan Severe Influenza Research Consortium)
Chang Gung Memorial Hospital · TWKaohsiung Medical University Chung-Ho Memorial Hospital · TWNational Taiwan University Hospital · TWNational Yang Ming Chiao Tung University · TWTaichung Veterans General Hospital · TWTri-Service General Hospital · TWCathay General Hospital · TWChina Medical University · TWKaohsiung Chang Gung Memorial Hospital · TWKaohsiung Medical University · TWTaipei Veterans General Hospital · TW

Funding

Cancer and Immunology Research Center 112W31101Ministry of Education, Higher Education SPROUT Project for Cancer Progression Research Center 111W31101National Science and Technology Council (Taiwan) NSTC 112-2314-B-075-050National Science and Technology Council (Taiwan) NSTC 112-2314-B-A49-040Taipei Veterans General Hospital V111B-024Taipei Veterans General Hospital V112B-031
6 · The paper itself

Abstract

backgroundPatients with influenza-related acute respiratory distress syndrome (ARDS) are critically ill and require mechanical ventilation (MV) support. Prolonged mechanical ventilation (PMV) is often seen in these cases and the optimal management strategy is not established. This study aimed to investigate risk factors for PMV and factors related to weaning failure in these patients.

methodsThis retrospective cohort study was conducted by eight medical centers in Taiwan. All patients in the intensive care unit with virology-proven influenza-related ARDS requiring invasive MV from January 1 to March 31, 2016, were included. Demographic data, critical illness data and clinical outcomes were collected and analyzed. PMV is defined as mechanical ventilation use for more than 21 days.

resultsThere were 263 patients with influenza-related ARDS requiring invasive MV enrolled during the study period. Seventy-eight patients had PMV. The final weaning rate was 68.8% during 60 days of observation. The mortality rate in PMV group was 39.7%. Risk factors for PMV were body mass index (BMI) > 25 (kg/m

conclusionsPatients with influenza-related ARDS and PMV have a high mortality rate. Risk factors for PMV include BMI > 25, ECMO use, combined bacterial pneumonia and neuromuscular blockade use over 48 h. In addition, ECMO use and bacteremia predict unsuccessful weaning in PMV patients.

Indexed as

BacteremiaInfluenza, HumanPneumonia, BacterialRespiratory Distress SyndromeCritical IllnessHumansRespiration, ArtificialRetrospective StudiesRisk Factors

Identifiers

PMID38178147
PMCPMC10765923
OpenAlexW4390584378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.