ArticleHealth research policy and systems2024
Learning health systems and evidence ecosystems: a perspective on the future of evidence-based medicine and evidence-based guideline development.
Article in Health research policy and systems, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Implementation Leadership in Evidence-Based Practice in Healthcare: A Systematic Review and Meta-Analysis.Worldviews on evidence-based nursing · 2026Pooled it
- Learning health system for implementation, scale-up, and sustainment: a systematic review to consolidate guidance for improvement.Implementation science : IS · 2026Pooled it
- Article
- Using informal caregivers' experience data to inform quality improvement in healthcare settings: a mixed-methods systematic review.BMC nursing · 2026Article
- Exploring Barriers, Enablers, and Strategies for Implementing Learning Health System Projects in Healthcare Organizations: A Multilevel Analysis in an Australian Setting.Learning health systems · 2026Article
- Implementing systems- and organisational-level change to advance gender equality in healthcare leadership: a mixed-methods implementation protocol.Implementation science communications · 2026Article
- Why evidence struggles to shape musculoskeletal health care and surgical practice in Australia: insights from an Australian clinician survey.BMC health services research · 2026Article
- The Monash learning health system maturity matrix: codesign of a tool to measure and guide improvement in complex health system behaviour.BMC health services research · 2026Article
- Mapping health evidence ecosystem in Brazil: a mixed-methods study protocol for developing a framework.Health research policy and systems · 2025Article
- CLEAR: A vision to support clinical evidence lifecycle with continuous learning.Journal of biomedical informatics · 2025Article
- Exploring implementation of interventions to facilitate integration in fragmented healthcare systems.Learning health systems · 2025Article
- Article
- Consumer and community involvement: implementation research for impact (CCIRI) - implementing evidence-based patient and public involvement across health and medical research in Australia - a mixed methods protocol.Health research policy and systems · 2025Article
- Automated citation searching in systematic review production: A simulation study.Research synthesis methods · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite forming the cornerstone of modern clinical practice for decades, implementation of evidence-based medicine at scale remains a crucial challenge for health systems. As a result, there has been a growing need for conceptual models to better contextualise and pragmatize the use of evidence-based medicine, particularly in tandem with patient-centred care. In this commentary, we highlight the emergence of the learning health system as one such model and analyse its potential role in pragmatizing both evidence-based medicine and patient-centred care. We apply the learning health system lens to contextualise the key activity of evidence-based guideline development and implementation, and highlight how current inefficiencies and bottlenecks in the evidence synthesis phase of evidence-based guideline development threaten downstream adherence. Lastly, we introduce the evidence ecosystem as a complementary model to learning health systems, and propose how innovative developments from the evidence ecosystem may be integrated with learning health systems to better enable health impact at speed and scale.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.