ArticleBMC musculoskeletal disorders2024
Adaptive Force of hamstring muscles is reduced in patients with knee osteoarthritis compared to asymptomatic controls.
Article in BMC musculoskeletal disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Effects of instrument-assisted soft tissue mobilization combined with exercise on knee joint muscle activity during walking in patients with moderate knee osteoarthritis: A randomized controlled clinical trial.Scientific reports · 2025Trial
- High prevalence of muscle stability deficits in semi-professional football players-Adaptive Force assessment reveals selective impairment of holding capacity with preserved maximal strength: A cross-sectional study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Article
- Three-dimensional artificial intelligence-based computed tomography analysis of lower limb muscle volume and fatty degeneration in varus and valgus knee osteoarthritis: a single-center retrospective study.BMC musculoskeletal disorders · 2026Article
- Reliability of quadriceps and hamstring muscle stiffness measured by ultrasound shear wave elastography in patients with knee osteoarthritis.BMC musculoskeletal disorders · 2026Article
- Integrated Bioinformatics and Experimental Validation Reveal Macrophage Polarization-Related Biomarkers for Osteoarthritis Diagnosis.Journal of multidisciplinary healthcare · 2025Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundQuadriceps strength deficits are known for patients with knee osteoarthritis (OA), whereas findings on hamstrings are less clear. The Adaptive Force (AF) as a special neuromuscular function has never been investigated in OA before. The maximal adaptive holding capacity (max. isometric AF; AFiso
methodsAF parameters and the maximal voluntary isometric contraction (MVIC) of hamstrings were assessed bilaterally comparing 20 patients with knee OA (ART) vs. controls (CON). AF was measured by a pneumatically driven device. Participants were instructed to maintain a static position despite an increasing load of the device. After reaching AFiso
resultsAFiso
conclusionThe results suggest that strength deficits of hamstrings are present in patients with knee OA possibly attributable to nociception, generally lower physical activity/relief of lower extremities or fear-avoidance. However, the more affected side of OA patients seems to show further specific impairments regarding neuromuscular control reflected by the significantly reduced adaptive holding capacity and torque development during adaptive eccentric action. It is assumed that those parameters could reflect possible inhibitory nociceptive effects more sensitive than maximal strengths as MVIC and AF
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