Evidence map›Paper›PMID 38177130›Full record

ArticleScientific data2024

Enrichment of lung cancer computed tomography collections with AI-derived annotations.

Deepa Krishnaswamy, Dennis Bontempi, Vamsi Krishna Thiriveedhi, Davide Punzo, David Clunie, Christopher P Bridge, Hugo J W L Aerts, Ron Kikinis, Andrey Fedorov

Abstract readDataset
In one paragraph

Article in Scientific data, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Multi-modal dataset creation for federated learning with DICOM-structured reports.International journal of computer assisted radiology and surgery · 2025
    Article
  4. Article
  5. Review
  6. National Cancer Institute Imaging Data Commons: Toward Transparency, Reproducibility, and Scalability in Imaging Artificial Intelligence.Radiographics : a review publication of the Radiological Society of North America, Inc · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Deepa KrishnaswamyBrigham and Women's Hospital, Boston, MA, USA. dkrishnaswamy@bwh.harvard.edu.
Dennis BontempiArtificial Intelligence in Medicine (AIM) Program, Mass General Brigham, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-0775-5679
Vamsi Krishna ThiriveedhiBrigham and Women's Hospital, Boston, MA, USA.
Davide PunzoRadical Imaging, Boston, MA, USA.
David CluniePixelMed Publishing, Bangor, PA, USA.ORCID 0000-0002-2406-1145
Christopher P BridgeDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0002-2242-351X
Hugo J W L AertsArtificial Intelligence in Medicine (AIM) Program, Mass General Brigham, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-2122-2003
Ron KikinisBrigham and Women's Hospital, Boston, MA, USA.
Andrey FedorovBrigham and Women's Hospital, Boston, MA, USA.

Funding

Training and DisseminationP41EB015902 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI KIKINIS, RON, WESTIN, CARL-FREDRIK · 2012 to 2022
$20.9M
Training in Image Guidance, Precision Diagnosis and TherapyT32EB025823 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI Fiona Fennessy, Lauren Jean O'Donnell · 2019 to 2026
$1.5M
NCI NIH HHS HHSN261201500003CNCI NIH HHS HHSN261201500003INIBIB NIH HHS P41 EB015902NIBIB NIH HHS T32 EB025823
6 · The paper itself

Abstract

Public imaging datasets are critical for the development and evaluation of automated tools in cancer imaging. Unfortunately, many do not include annotations or image-derived features, complicating downstream analysis. Artificial intelligence-based annotation tools have been shown to achieve acceptable performance and can be used to automatically annotate large datasets. As part of the effort to enrich public data available within NCI Imaging Data Commons (IDC), here we introduce AI-generated annotations for two collections containing computed tomography images of the chest, NSCLC-Radiomics, and a subset of the National Lung Screening Trial. Using publicly available AI algorithms, we derived volumetric annotations of thoracic organs-at-risk, their corresponding radiomics features, and slice-level annotations of anatomical landmarks and regions. The resulting annotations are publicly available within IDC, where the DICOM format is used to harmonize the data and achieve FAIR (Findable, Accessible, Interoperable, Reusable) data principles. The annotations are accompanied by cloud-enabled notebooks demonstrating their use. This study reinforces the need for large, publicly accessible curated datasets and demonstrates how AI can aid in cancer imaging.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsArtificial IntelligenceHumansLungTomography, X-Ray Computed

Identifiers

PMID38177130
PMCPMC10766991

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.