Evidence map›Paper›PMID 38177041›Full record

ReviewTrends in genetics : TIG2024

Gene regulation during meiosis.

Jingyi Gao, Yiwen Qin, John C Schimenti

Open access · greenAbstract readReview
In one paragraph

Review in Trends in genetics : TIG, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Identification of a master regulator Msd1 that governs meiotic entry in a global basidiomycete pathogen.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Deletion ofBiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jingyi GaoCornell University, College of Veterinary Medicine, Department of Biomedical Sciences, Ithaca, NY 14853, USA.
Yiwen QinCornell University, College of Veterinary Medicine, Department of Biomedical Sciences, Ithaca, NY 14853, USA.
John C SchimentiCornell University, College of Veterinary Medicine, Department of Biomedical Sciences, Ithaca, NY 14853, USA. Electronic address: jcs92@cornell.edu.
Cornell University · US

Funding

Project IIIP50HD096723 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Kyle Edwin Orwig · 2019 to 2026
$15.0M
Spermatogenic gene regulation and infertilityP50HD104454 · NICHD · CORNELL UNIVERSITY · PI GRENIER, JENNIFER K · 2021 to 2025
$8.1M
Identification and Functional Validation of Human Infertility AllelesR01HD082568 · NICHD · CORNELL UNIVERSITY · PI SCHIMENTI, JOHN C · 2015 to 2024
$6.0M
Mechanisms underlying sex-dependent pregnancy outcomes caused by fetal and maternal genomic instabilityR01HD107910 · NICHD · CORNELL UNIVERSITY · PI John C Schimenti · 2022 to 2026
$1.7M
NICHD NIH HHS P50 HD096723NICHD NIH HHS P50 HD104454NICHD NIH HHS R01 HD082568NICHD NIH HHS R01 HD107910
6 · The paper itself

Abstract

Meiosis is essential for gamete production in all sexually reproducing organisms. It entails two successive cell divisions without DNA replication, producing haploid cells from diploid ones. This process involves complex morphological and molecular differentiation that varies across species and between sexes. Specialized genomic events like meiotic recombination and chromosome segregation are tightly regulated, including preparation for post-meiotic development. Research in model organisms, notably yeast, has shed light on the genetic and molecular aspects of meiosis and its regulation. Although mammalian meiosis research faces challenges, particularly in replicating gametogenesis in vitro, advances in genetic and genomic technologies are providing mechanistic insights. Here we review the genetics and molecular biology of meiotic gene expression control, focusing on mammals.

Indexed as

MeiosisSaccharomyces cerevisiaeAnimalsChromosome SegregationDNA ReplicationGametogenesisMammalsenhancersmeiotic initiationpost-transcriptional regulationrecombinationretinoic acid signalingtranscription

Identifiers

PMID38177041
PMCPMC11003842
OpenAlexW4390585373

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.