Evidence map›Paper›PMID 38176890›Full record

ArticleJournal of intensive care medicine2024

Postarrest Care Bundle Improves Quality of Care and Clinical Outcomes in the Normothermia Era.

Andrew J Caddell, Dave Nagpal, Ahmed F Hegazy

Abstract read
In one paragraph

Article in Journal of intensive care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Andrew J CaddellCardiology Division, Dalhousie University, Halifax, Nova Scotia, Canada.ORCID 0000-0002-9025-3233
Dave NagpalCritical Care, Western University, London, Ontario, Canada.
Ahmed F HegazyCritical Care, Western University, London, Ontario, Canada.ORCID 0000-0001-9998-8968

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTemperature targets in patients with cardiac arrest and return of spontaneous circulation (ROSC) have changed. Changes to higher temperature targets have been associated with higher breakthrough fevers and mortality. A post-ROSC normothermia bundle was developed to improve compliance with temperature targets.

methodsIn August 2021, "ad hoc" normothermia at the discretion of the attending intensivist was initiated. In December 2021, a post-ROSC normothermia protocol was implemented, incorporating a rigorous, stepwise approach to fever prevention (temperature ≥ 37.8). We conducted a before-after cohort study of all adult patients post-ROSC who survived to intensive care unit admission between August 1, 2021, and April 1, 2022. They were divided into "ad hoc" and "protocol" groups. Clinical outcomes compared included fevers, active cooling, and paralytic use.

resultsFifty-eight post-ROSC patients were admitted; 24 in the "ad hoc" and 34 in the "protocol" groups. Patient demographics were similar between groups. The "ad hoc" group had more shockable rhythms (67% vs 24%,

conclusionUse of a normothermia "protocol" resulted in fewer fevers and less neuromuscular blocker administration compared to "ad hoc" management. A protocolized approach for improved quality of care should be considered in institutions adopting normothermia.

Indexed as

FeverPatient Care BundlesAgedBody TemperatureCardiopulmonary ResuscitationClinical ProtocolsCritical CareFemaleHeart ArrestHumansIntensive Care UnitsMaleMiddle AgedQuality ImprovementTreatment Outcomecardiac arrestnormothermiaquality improvementtemperature management

Identifiers

PMID38176890
PMCPMC11149385

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.