ReviewUltrasonics sonochemistry2024
Recent developments using malononitrile in ultrasound-assisted multicomponent synthesis of heterocycles.
Review in Ultrasonics sonochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Multicomponent Reactions for the Synthesis of Oxazepines.Topics in current chemistry (Cham) · 2026Review
- A novel copper-based magnetic nano catalyst for the synthesis of hexahydroquinolines, aminocyanopyridines, and pyranopyrazoles.Scientific reports · 2026Article
- ZnFeChemistryOpen · 2026Article
- Ball-mill-assisted mechanochemical approaches for heterocyclic compound synthesis (2015-2024).Molecular diversity · 2026Review
- Article
- Review
- FeBMC chemistry · 2025Article
- Magnetically recoverable catalysts for efficient multicomponent synthesis of organosulfur compounds.RSC advances · 2025Review
- Multi-omics reveals the regulatory effects of Chinese herbal medicine substrates on secondary metabolite biosynthesis inFrontiers in microbiology · 2025Article
- Recent Advances in the Application of 2-Aminobenzothiazole to the Multicomponent Synthesis of Heterocycles.ChemistryOpen · 2024Review
- A Ru-Based Complex for Sustainable One-Pot Tandem Aerobic Oxidation-Knoevenagel Condensation Reactions.Molecules (Basel, Switzerland) · 2024Article
- Efficient Synthesis, Structural Characterization, Antibacterial Assessment, ADME-Tox Analysis, Molecular Docking and Molecular Dynamics Simulations of New Functionalized Isoxazoles.Molecules (Basel, Switzerland) · 2024Article
- Recent advances in microwave-assisted multicomponent synthesis of spiro heterocycles.RSC advances · 2024Review
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2 authors.
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Abstract
Ultrasonic irradiation serves as a vigorous and environmentally sustainable approach for augmenting multicomponent reactions (MCRs), offering benefits such as thermal enhancement, agitation, and activation, among others. Malononitrile emerges as a versatile reagent in this context, participating in a myriad of MCRs to produce structurally diverse heterocyclic frameworks. This review encapsulates the critical role of malononitrile in the sonochemical multicomponent synthesis of these heterocyclic structures. The paper further delves into the biochemical and pharmacological implications of these heterocycles, elucidating their reaction mechanisms as well as delineating the method's scope and limitations. We furnish an overview of the merits and challenges inherent to this synthetic approach and offer insights for potential avenues in future research.
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